{"id":"W4309244247","doi":"10.1097/txd.0000000000001406","title":"Anti-interleukin-6 Antibody Clazakizumab in Antibody-mediated Kidney Transplant Rejection: Effect on Donor-derived Cell-free DNA and C-X-C Motif Chemokine Ligand 10","year":2022,"lang":"en","type":"article","venue":"Transplantation Direct","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"","keywords":"Medicine; Interquartile range; Creatinine; Internal medicine; Antibody; Immunology; Chemokine; Placebo; Gastroenterology; Endocrinology; Inflammation; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00177502,0.0006853156,0.001436931,0.0003054974,0.0002165348,0.0005188464,0.0004511173,0.0006267652,0.001382826],"category_scores_gemma":[0.0007673542,0.0002850025,0.0007852565,0.0001840015,0.0005636603,0.0004469597,0.000202997,0.001740464,0.0002590278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005384527,"about_ca_system_score_gemma":0.0008092857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003713217,"about_ca_topic_score_gemma":0.00159231,"domain_scores_codex":[0.9995207,0.0002186462,0.0000449671,0.00006352211,0.00006278788,0.00008952178],"domain_scores_gemma":[0.9992802,0.0001551296,0.0002203324,0.00004680776,0.00005734935,0.0002402455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5325891,0.02523462,0.007682231,0.001742043,0.001528936,0.0001698492,0.0001518144,0.001277749,0.268535,0.0002441308,0.001436011,0.1594085],"study_design_scores_gemma":[0.2841325,0.613924,0.03900795,0.0001668856,0.001940165,0.0005627751,0.00007302063,0.002391387,0.05430505,0.0001750224,0.003271158,0.00005013276],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942995,0.004579628,0.0002669934,0.0001894441,0.00007121642,0.0001669987,0.000059033,0.00001835321,0.0003486997],"genre_scores_gemma":[0.9968538,0.00166075,0.0005527894,0.0001803026,0.0001163521,0.0001481577,0.0001005351,0.000004709366,0.0003826586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00177502,"threshold_uncertainty_score":0.009387374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009883517151941742,"score_gpt":0.2704516861973411,"score_spread":0.2605681690453994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}