{"id":"W4309362540","doi":"10.46747/cfp.6811807","title":"Individualized antidepressant therapy in patients with major depressive disorder","year":2022,"lang":"en","type":"review","venue":"Canadian Family Physician","topic":"Treatment of Major Depression","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"South Health Campus; Alberta Health; College of Family Physicians of Canada; Alberta Health Services","funders":"","keywords":"Major depressive disorder; Antidepressant; Medicine; Context (archaeology); Psychiatry; Discontinuation; Mood; Depression (economics); Pharmacotherapy; Anxiety; Bupropion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001827807,0.0005356041,0.0005162629,0.0007386646,0.0010722,0.001635583,0.0008136821,0.0007456079,0.01337051],"category_scores_gemma":[0.01413384,0.0001709502,0.0006471484,0.0005464111,0.0002712655,0.0006852614,0.00107099,0.001015136,0.001841714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003123585,"about_ca_system_score_gemma":0.007133505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05106662,"about_ca_topic_score_gemma":0.1784684,"domain_scores_codex":[0.9988739,0.0004353977,0.0001516653,0.00009184932,0.0003619503,0.00008513692],"domain_scores_gemma":[0.997381,0.001166373,0.0003828737,0.00008716367,0.0005601631,0.0004224141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001009778,0.0003668753,0.03557941,0.0010938,0.0001543852,0.0007797224,0.0009397277,0.002670204,0.0006965591,0.002484121,0.2616786,0.6925468],"study_design_scores_gemma":[0.004142844,0.001418679,0.1355736,0.005789058,0.001248554,0.003722482,0.003167897,0.03666824,0.004141716,0.02594486,0.7775668,0.0006153403],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.2474778,0.03915035,0.06661541,0.2277303,0.005754322,0.004595779,0.01643125,0.01367342,0.3785714],"genre_scores_gemma":[0.749377,0.01362268,0.1872381,0.02069718,0.001647048,0.001241132,0.004069841,0.0003522891,0.02175471],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.05106662,"threshold_uncertainty_score":0.1015387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02842392712558539,"score_gpt":0.2794078812392197,"score_spread":0.2509839541136343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}