{"id":"W4309365766","doi":"10.1017/cjn.2022.324","title":"A Quality Assessment of Aquaporin-4 & Myelin Oligodendrocyte Glycoprotein Antibody Testing","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; Ontario Brain Institute; University of Calgary","funders":"Sanofi Genzyme; EMD Serono; Multiple Sclerosis Society of Canada; University of Calgary; Alberta Health Services; Alexion Pharmaceuticals; Alberta Precision Laboratories; Sanofi; Biogen; Bristol-Myers Squibb","keywords":"Neuromyelitis optica; Myelin oligodendrocyte glycoprotein; Medicine; Autoantibody; Concordance; Aquaporin 4; Internal medicine; Multiple sclerosis; Immunology; Antibody; Experimental autoimmune encephalomyelitis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02575104,0.0002993419,0.0005457818,0.004584258,0.000687065,0.001932804,0.00130162,0.0003247908,0.001094037],"category_scores_gemma":[0.07160538,0.0002798559,0.0007802682,0.004516834,0.0009924714,0.0008487757,0.001925162,0.0004399903,0.0002100745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00385134,"about_ca_system_score_gemma":0.003302295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02178763,"about_ca_topic_score_gemma":0.01112905,"domain_scores_codex":[0.9703236,0.008552738,0.005934241,0.002510677,0.01175971,0.0009190189],"domain_scores_gemma":[0.8738394,0.02041971,0.05854188,0.006758852,0.03762015,0.002820017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001243708,0.00001806535,0.9880289,0.00008217359,0.00008938473,0.00004221125,0.0002666495,0.0002649316,0.0002197697,0.00006501253,0.0004454093,0.01035302],"study_design_scores_gemma":[0.00001789686,0.0003980907,0.9933712,0.0001045523,0.00008571948,0.0005116797,0.0004671964,0.002403571,0.0008677517,0.00009725618,0.001661276,0.00001371054],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764837,0.002536749,0.01000679,0.0008328432,0.00009502279,0.0006309008,0.003774588,0.0001201235,0.005519224],"genre_scores_gemma":[0.9956938,0.0002316115,0.002660572,0.00006867098,0.00002905487,0.00009753983,0.001034026,0.00001327975,0.0001714356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02575104,"threshold_uncertainty_score":0.1361861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1660649076192835,"score_gpt":0.4034036058838604,"score_spread":0.2373386982645769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}