{"id":"W4309460469","doi":"10.3390/pharmaceutics14112497","title":"Amphotericin B- and Levofloxacin-Loaded Chitosan Films for Potential Use in Antimicrobial Wound Dressings: Analytical Method Development and Its Application","year":2022,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Nanocomposite Films for Food Packaging","field":"Materials Science","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University Belfast; Queen's University; Wellcome Trust; Wellcome","keywords":"Chitosan; Antimicrobial; Levofloxacin; Amphotericin B; Ex vivo; Staphylococcus aureus; Candida albicans; Microbiology; Permeation; Chromatography; Chemistry; In vivo; Antibacterial agent; Materials science; Antibiotics; Antifungal; In vitro; Bacteria; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000561634,0.0001922604,0.0002565989,0.0001813453,0.0004066332,0.0001691748,0.0001726942,0.00004765553,0.00003571732],"category_scores_gemma":[0.00002080106,0.000213027,0.00003078194,0.0002462325,0.0000499313,0.0002365157,0.0003389505,0.0002021561,0.000002811099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006463211,"about_ca_system_score_gemma":0.00006569719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001968807,"about_ca_topic_score_gemma":0.000003697163,"domain_scores_codex":[0.9983826,0.0001368767,0.0003752655,0.000484107,0.0002278802,0.0003932732],"domain_scores_gemma":[0.9994705,0.0001157699,0.0001347964,0.0001314962,0.00002696148,0.0001204203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001941514,0.00009480835,0.0006897888,0.00007941653,0.00001462961,0.000008104303,0.0008867914,0.0007293328,0.9953851,0.00007797087,0.00007241013,0.001767502],"study_design_scores_gemma":[0.001472521,0.00003445218,0.0007954318,0.00001401868,0.00005937797,0.00007161997,0.0001009744,0.05588511,0.9370236,0.0000224696,0.004261822,0.000258583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866297,0.0001566551,0.01179839,0.0002097239,0.0002505715,0.0007904635,0.00009189185,0.00005278361,0.00001983595],"genre_scores_gemma":[0.9569462,0.00001134242,0.04234557,0.0004308859,0.00004304131,0.0001081494,0.00005308116,0.00002945865,0.00003228891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05836147,"threshold_uncertainty_score":0.8686987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05339520212020864,"score_gpt":0.3436441192355011,"score_spread":0.2902489171152924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}