{"id":"W4309508403","doi":"10.15252/embr.202255420","title":"Composition, organization and mechanisms of the transition zone, a gate for the cilium","year":2022,"lang":"en","type":"review","venue":"EMBO Reports","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Cilium; Intraflagellar transport; Axoneme; Biology; Cell biology; Ciliopathy; Ciliopathies; Ciliogenesis; Endocytic cycle; Compartmentalization (fire protection); Membrane curvature; Transport protein; Endocytosis; Flagellum; Vesicle; Cell; Genetics; Biochemistry; Membrane; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000165625,0.0001422196,0.0002647602,0.00001612747,0.0001811353,0.00001274942,0.0001003709,0.00009816526,0.00004680295],"category_scores_gemma":[0.00006561099,0.00008587563,0.0001872442,0.000108116,0.00004640129,0.000001045261,0.00007403178,0.00005179461,1.696587e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008751383,"about_ca_system_score_gemma":0.0002281812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003798962,"about_ca_topic_score_gemma":0.000001141337,"domain_scores_codex":[0.9991473,0.0000783104,0.0003175531,0.0002497103,0.00011924,0.00008790853],"domain_scores_gemma":[0.9991752,0.000022706,0.0003235472,0.0003751554,0.00007010299,0.00003327608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002214281,0.001481395,0.00006418358,0.07326306,0.005496224,0.0001693349,0.001173136,0.0008067232,0.07443921,0.003576024,0.06788654,0.7714227],"study_design_scores_gemma":[0.00009800877,0.00007500432,0.00002378011,0.0002501535,0.0009882095,0.0005342428,0.00003509703,0.000005584352,0.002737364,0.0004014156,0.994696,0.000155141],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001911408,0.9747707,0.0230995,0.00008248464,0.0004009158,0.001229336,0.0001495107,0.000007044247,0.00006942833],"genre_scores_gemma":[0.009295451,0.9884287,0.0001133097,0.0001495194,0.0001164445,0.0001853772,0.001422671,0.00003906157,0.0002495066],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9268094,"threshold_uncertainty_score":0.3501907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293438915852241,"score_gpt":0.251299060186463,"score_spread":0.2383646710279406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}