{"id":"W4309524066","doi":"10.3389/ti.2022.10772","title":"Autologous Mesenchymal Stem Cells for Treatment of Chronic Active Antibody-Mediated Kidney Graft Rejection: Report of the Phase I/II Clinical Trial Case Series","year":2022,"lang":"en","type":"article","venue":"Transplant International","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"Javna Agencija za Raziskovalno Dejavnost RS","keywords":"Medicine; Mesenchymal stem cell; Adverse effect; Biopsy; Kidney transplantation; Transplantation; Clinical trial; Kidney; Surgery; Clinical endpoint; Kidney disease; Internal medicine; Urology; Oncology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006901893,0.0001772784,0.0005369615,0.000144422,0.00022188,0.000006038937,0.0002172865,0.00009705892,0.001087362],"category_scores_gemma":[0.00009838662,0.000125954,0.0004717019,0.000204743,0.0002128671,0.00006363156,0.00005608109,0.0002089732,0.000002000804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000377754,"about_ca_system_score_gemma":0.00118383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001977657,"about_ca_topic_score_gemma":0.00004783275,"domain_scores_codex":[0.9972922,0.0002427277,0.001018814,0.0003818251,0.0008195888,0.0002448348],"domain_scores_gemma":[0.9983131,0.0004848482,0.0004341732,0.0003468216,0.0002643187,0.0001567242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.5593518,0.0333645,0.009053072,0.001035995,0.006880169,0.03959379,0.005072246,0.0003343126,0.3008481,0.001448418,0.003754539,0.03926305],"study_design_scores_gemma":[0.2873707,0.08714572,0.0009311911,0.0003084274,0.001336399,0.08775239,0.0008655305,0.008061772,0.3883784,0.0000679039,0.1372573,0.0005242877],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892046,0.00007339923,0.0001944359,0.001623592,0.002707344,0.002352673,0.002929289,0.00002994842,0.0008846513],"genre_scores_gemma":[0.9918657,0.0001448691,0.00009325614,0.00002800086,0.0004180673,0.0002593303,0.0007805936,0.00002068204,0.0063895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2719811,"threshold_uncertainty_score":0.9998258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08155714433456562,"score_gpt":0.4141903522970758,"score_spread":0.3326332079625102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}