{"id":"W4309566567","doi":"10.1016/j.pestbp.2022.105295","title":"Topical delivery of dsRNA in two hemipteran species: Evaluation of RNAi specificity and non-target effects","year":2022,"lang":"en","type":"article","venue":"Pesticide Biochemistry and Physiology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Regione Emilia-Romagna","keywords":"Biology; Rhodnius prolixus; Nymph; RNA silencing; RNA interference; Gene silencing; Instar; RNA; Botany; Gene; Biochemistry; Insect; Larva","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002124759,0.0003480867,0.0003112837,0.0002801375,0.0002292622,0.0002863109,0.0002489786,0.0006037177,0.001318006],"category_scores_gemma":[0.0002381145,0.0002035011,0.0002633769,0.0001300786,0.0002188726,0.0003561767,0.0001486137,0.0007542188,0.000261353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003429359,"about_ca_system_score_gemma":0.0002206743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008612075,"about_ca_topic_score_gemma":0.00159477,"domain_scores_codex":[0.9998554,0.00002168418,0.00001328256,0.00004939489,0.00002862609,0.00003167665],"domain_scores_gemma":[0.9997259,0.00008768454,0.00005280906,0.00002941277,0.00004718962,0.00005698852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004238374,0.0000128602,0.00002497407,0.000009960276,0.000001150933,0.000007807755,0.000004140834,0.000006987022,0.9996225,0.00001136049,0.000004876565,0.0002510073],"study_design_scores_gemma":[0.000009770436,0.000588293,0.001465532,0.000001891466,0.000019043,0.00006784226,0.0000171144,0.0002595095,0.9972206,0.000008104342,0.0003392852,0.000003090752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930947,0.0009894845,0.004117519,0.00007217967,0.00004460469,0.0001061998,0.0002344524,0.00008134363,0.001259497],"genre_scores_gemma":[0.9804792,0.00119535,0.01035775,0.000133231,0.00002606883,0.0001689174,0.0007557298,0.00008559201,0.006798121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001318006,"threshold_uncertainty_score":0.004409194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009249845792717103,"score_gpt":0.2594295803446744,"score_spread":0.2501797345519573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}