{"id":"W4309637538","doi":"10.1002/btm2.10454","title":"Integrated role of human thymic stromal cells in hematopoietic stem cell extravasation","year":2022,"lang":"en","type":"article","venue":"Bioengineering & Translational Medicine","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"H2020 European Research Council; NIHR Great Ormond Street Hospital Biomedical Research Centre; Research England; Innovate UK; Cancer Research UK; Horizon 2020 Framework Programme; Medical Research Council; Directorate for Biological Sciences; Biotechnology and Biological Sciences Research Council; Rosetrees Trust; Engineering and Physical Sciences Research Council; Leverhulme Trust; National Institute for Health and Care Research; Francis Crick Institute","keywords":"Stromal cell; Extravasation; Haematopoiesis; Biology; Stem cell; Cell biology; Bone marrow; Extracellular matrix; Leukocyte extravasation; Hematopoietic stem cell; CD34; Immunology; Cancer research; Cell adhesion molecule","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003894311,0.0002125289,0.000436741,0.000502174,0.00006117531,0.000003160076,0.0001171554,0.0000717111,0.0006588315],"category_scores_gemma":[0.00000359543,0.000208831,0.0000778597,0.0005830544,0.00006621412,0.00005716351,0.000009484776,0.0003290764,0.000004847088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067951,"about_ca_system_score_gemma":0.00009862795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009200161,"about_ca_topic_score_gemma":0.000005541208,"domain_scores_codex":[0.9979813,0.00006181263,0.0007349638,0.0002798234,0.0007003823,0.0002416993],"domain_scores_gemma":[0.9994134,0.0001261542,0.000110175,0.0001999392,0.00006363555,0.00008666649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001191038,0.0001955903,0.004482668,0.000553204,0.00003038169,0.00002963424,0.004429426,0.006134862,0.9818859,0.001221145,0.00001961649,0.0008984437],"study_design_scores_gemma":[0.020605,0.003561606,0.1514244,0.002295162,0.0006927867,0.000526058,0.0138792,0.06038899,0.7416291,0.0008450592,0.003006586,0.001146011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916722,0.001291451,0.004483222,0.0003666669,0.0001957275,0.0006074092,0.00006098403,0.00008662042,0.001235724],"genre_scores_gemma":[0.9985732,0.00001924522,0.0007583465,0.00003069418,0.00005307355,0.00006238611,0.0003312874,0.00003993306,0.000131797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2402568,"threshold_uncertainty_score":0.8515882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01622850330155795,"score_gpt":0.2391582074454244,"score_spread":0.2229297041438664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}