{"id":"W4309658164","doi":"10.1200/jco.22.01632","title":"Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD)","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Adverse effect; Cannabidiol; Anxiety; Distress; Depression (economics); Quality of life (healthcare); Opioid; Randomized controlled trial; Nausea; Internal medicine; Anesthesia; Psychiatry; Cannabis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01911579,0.0002211613,0.00448093,0.0003795797,0.0001279424,0.000008012271,0.0005071771,0.0002155572,0.0004601231],"category_scores_gemma":[0.006965357,0.0001300661,0.001305302,0.0004824753,0.0004654623,0.00007316377,0.0001887829,0.001882681,3.942628e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003730859,"about_ca_system_score_gemma":0.004749572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008372609,"about_ca_topic_score_gemma":0.001154122,"domain_scores_codex":[0.9910801,0.001721013,0.005285307,0.0003160882,0.001159635,0.0004378327],"domain_scores_gemma":[0.9898265,0.004290216,0.004042429,0.0004042257,0.001130369,0.0003062602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.849043,0.01209463,0.002041637,0.00008599905,0.00129867,0.00010052,0.0009153415,0.002818301,0.0002696411,0.00005965322,0.006581536,0.1246911],"study_design_scores_gemma":[0.9232266,0.04073513,0.001482987,0.00009225705,0.001107143,0.00006499191,0.003083783,0.001475496,0.00007994237,0.00004945611,0.02848955,0.0001126744],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737078,0.003037322,0.00003023481,0.01742303,0.001512724,0.003538342,0.00002312122,0.000004725172,0.0007227328],"genre_scores_gemma":[0.9912024,0.0009852329,0.00009528705,0.0005522969,0.0007193586,0.001563108,0.000002693354,0.00003510643,0.00484458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1245784,"threshold_uncertainty_score":0.8425537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1027683490991425,"score_gpt":0.5042183069792973,"score_spread":0.4014499578801548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}