{"id":"W4309658164","doi":"10.1200/jco.22.01632","title":"Phase IIb Randomized, Placebo-Controlled, Dose-Escalating, Double-Blind Study of Cannabidiol Oil for the Relief of Symptoms in Advanced Cancer (MedCan1-CBD)","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Adverse effect; Cannabidiol; Anxiety; Distress; Depression (economics); Quality of life (healthcare); Opioid; Randomized controlled trial; Nausea; Internal medicine; Anesthesia; Psychiatry; Cannabis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001818549,0.00175463,0.003802241,0.000566211,0.0006205417,0.0008409715,0.001063277,0.001944057,0.006968734],"category_scores_gemma":[0.001804021,0.0008846877,0.0009448062,0.0005887937,0.001192419,0.0007079,0.0003438539,0.001840075,0.001433486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009213884,"about_ca_system_score_gemma":0.002009116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001468654,"about_ca_topic_score_gemma":0.003608922,"domain_scores_codex":[0.9993819,0.0002988313,0.0000484617,0.0001079549,0.00005852325,0.0001043483],"domain_scores_gemma":[0.9992983,0.0001621848,0.0001899,0.00007166441,0.00007512436,0.0002027816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9475368,0.01543938,0.0005577718,0.001081099,0.0004796713,0.0000444923,0.00006405626,0.0003350079,0.008691669,0.0001265135,0.001246867,0.02439656],"study_design_scores_gemma":[0.9256074,0.0715767,0.001155637,0.00003025925,0.0001598894,0.00002089009,0.00001560506,0.0002701949,0.0004928004,0.00008433522,0.0005761115,0.00001012862],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9586962,0.005495585,0.001848078,0.0008912645,0.0007921819,0.02532037,0.002590082,0.0004245423,0.003941691],"genre_scores_gemma":[0.9535094,0.004337476,0.006041202,0.002479541,0.0006363579,0.02522754,0.00182853,0.00005733533,0.005882563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006968734,"threshold_uncertainty_score":0.02331275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1027683490991425,"score_gpt":0.5042183069792973,"score_spread":0.4014499578801548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}