{"id":"W4309688493","doi":"10.3390/antiox11112302","title":"Myeloperoxidase: Regulation of Neutrophil Function and Target for Therapy","year":2022,"lang":"en","type":"review","venue":"Antioxidants","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"Myeloperoxidase; Azurophilic granule; Neutrophil extracellular traps; Innate immune system; Cell biology; Phagocytosis; Biology; Immune system; Immunity; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004377011,0.0005479472,0.001681288,0.0003857575,0.0003505008,0.00001724862,0.0003066343,0.0004727303,0.001527612],"category_scores_gemma":[0.00003726232,0.0004557814,0.0004705525,0.000351348,0.0001730905,0.0001479403,0.0001542878,0.0003983291,0.00005816626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005058421,"about_ca_system_score_gemma":0.000155256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002368749,"about_ca_topic_score_gemma":0.000001645409,"domain_scores_codex":[0.9975019,0.000466861,0.0008172993,0.0007147478,0.00008162513,0.0004176244],"domain_scores_gemma":[0.9983714,0.000313113,0.000707611,0.0004847905,0.00009100346,0.00003210959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002102987,0.0001785715,0.000004199606,0.00281853,0.00068218,0.000002041606,0.00004533705,3.559335e-7,0.04812339,0.004056588,0.0006632046,0.9432153],"study_design_scores_gemma":[0.001290342,0.0009643912,0.00008759446,0.0007816344,0.0004021093,0.00004909101,0.00002935955,4.227999e-7,0.005382303,0.001330237,0.9892457,0.0004368309],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001591554,0.9947022,0.000342656,0.00002507333,0.000985655,0.001669563,0.0004606807,0.00006961454,0.0001529557],"genre_scores_gemma":[0.001044468,0.9947873,0.0001921627,0.00006845598,0.0001026961,0.0004150742,0.001451876,0.000102421,0.001835486],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9885825,"threshold_uncertainty_score":0.9997894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06325448476815412,"score_gpt":0.2991041119103884,"score_spread":0.2358496271422343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}