{"id":"W4309739673","doi":"10.3390/tropicalmed7110384","title":"Investigating the Leishmania donovani sacp Gene and Its Role in Macrophage Infection and Survival in Mice","year":2022,"lang":"en","type":"article","venue":"Tropical Medicine and Infectious Disease","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; R. Howard Webster Foundation","keywords":"Leishmania donovani; Biology; Amastigote; Gene; Virulence; Spleen; Leishmania; Genetics; Leishmaniasis; Parasite hosting; Visceral leishmaniasis; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004743055,0.000608149,0.000457329,0.0009090175,0.0003562076,0.0005078974,0.0005858758,0.00124137,0.002315559],"category_scores_gemma":[0.0002089293,0.0003994512,0.0005983262,0.00031439,0.0006742766,0.0005684342,0.0004537993,0.002427219,0.001041078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000492744,"about_ca_system_score_gemma":0.000367975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006517681,"about_ca_topic_score_gemma":0.0007007485,"domain_scores_codex":[0.9995375,0.00006601889,0.00004215879,0.0001241956,0.000111088,0.0001191326],"domain_scores_gemma":[0.9996699,0.00004641533,0.00009190814,0.00003574263,0.0000394127,0.0001165798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000260368,0.0001017964,0.0002270084,0.00007994824,0.000008532645,0.0001090956,0.00005308344,0.00007872805,0.9973215,0.0003803928,0.0000912323,0.001288293],"study_design_scores_gemma":[0.0001332311,0.001236755,0.005012246,0.00004319974,0.00006537671,0.0007838433,0.0001516923,0.001944928,0.9804872,0.0003173962,0.009805147,0.0000190665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660316,0.003676802,0.01823932,0.001359482,0.0002337994,0.0002213243,0.004394506,0.0004316433,0.005411426],"genre_scores_gemma":[0.9679833,0.002543598,0.0107083,0.0004997143,0.00004133966,0.0005956966,0.003017547,0.0001848772,0.01442574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002315559,"threshold_uncertainty_score":0.007746279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0244617216006459,"score_gpt":0.2938715646242163,"score_spread":0.2694098430235704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}