{"id":"W4309845676","doi":"10.3390/cells11233742","title":"Terminal Uridylyltransferases TUT4/7 Regulate microRNA and mRNA Homeostasis","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; J.P. Bickell Foundation","keywords":"microRNA; Biology; Cell biology; Transcriptome; Messenger RNA; Biogenesis; P-bodies; Gene silencing; Translation (biology); Genetics; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001326389,0.00008914807,0.00008712213,0.00003762461,0.0002002495,0.00002624963,0.0001368078,0.00003110229,0.0001271596],"category_scores_gemma":[0.000007857615,0.000089324,0.00004858353,0.00005798973,0.00006327397,0.000002112866,0.0001479729,0.00009953372,0.000005285575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001024684,"about_ca_system_score_gemma":0.00004162097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003151654,"about_ca_topic_score_gemma":0.000005935255,"domain_scores_codex":[0.9992474,0.00005442433,0.00009727565,0.0002455424,0.0001191551,0.0002362418],"domain_scores_gemma":[0.9996642,0.000008966957,0.0000185548,0.0001945554,0.00001731783,0.00009633611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007638775,0.00002684237,0.0003681971,0.00001445619,0.00001762081,0.00003626182,0.00002881343,0.00001854367,0.9868273,0.000006829282,0.004422824,0.008155916],"study_design_scores_gemma":[0.0003854827,0.0003089205,0.0008607451,0.000003530317,0.000008050863,0.00008008306,0.0001074739,0.00003593498,0.9016069,0.00002138711,0.09644628,0.0001351845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972188,0.001886009,0.00005653197,0.0001928645,0.00006719519,0.000102481,0.00005661821,0.000007086371,0.0004124455],"genre_scores_gemma":[0.9940228,0.000490136,0.0001378204,0.0002437178,0.00007763583,0.00001722255,0.00004996054,0.00001501263,0.004945674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09202346,"threshold_uncertainty_score":0.3642527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008523282585989066,"score_gpt":0.2362784595176503,"score_spread":0.2277551769316613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}