{"id":"W4309928804","doi":"10.1016/j.virs.2022.11.006","title":"OGG1 inhibition suppresses African swine fever virus replication","year":2022,"lang":"en","type":"article","venue":"Virologica Sinica","topic":"Animal Disease Management and Epidemiology","field":"Agricultural and Biological Sciences","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Agricultural Science and Technology Innovation Program; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences; National Key Research and Development Program of China; Chinese Academy of Agricultural Sciences; Natural Science Foundation of Gansu Province; Chinese Academy of Sciences; State Key Laboratory of Veterinary Etiological Biology; Institute of Genetics; National Natural Science Foundation of China","keywords":"African swine fever virus; Biology; DNA glycosylase; Viral replication; Virology; Base excision repair; Virus; DNA; DNA damage; Interferon; Reactive oxygen species; Molecular biology; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001187996,0.0003398,0.0003631536,0.0001724095,0.0001300055,0.0002025852,0.0002307435,0.0003018164,0.00120941],"category_scores_gemma":[0.0001119145,0.0001007725,0.000273257,0.000115886,0.0001868944,0.0001503146,0.0001635303,0.0007078103,0.0002557849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001576631,"about_ca_system_score_gemma":0.0002294397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006451698,"about_ca_topic_score_gemma":0.0008614,"domain_scores_codex":[0.9998853,0.00002031959,0.00001102267,0.00001948522,0.00001844766,0.0000453784],"domain_scores_gemma":[0.9999378,0.00001031257,0.00001419299,0.000007691199,0.000008264163,0.00002183634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00148397,0.0003630634,0.0002843113,0.0001253191,0.00001629432,0.00005053958,0.000032246,0.000103983,0.9922207,0.00008821651,0.0002779126,0.004953369],"study_design_scores_gemma":[0.0001360756,0.004596986,0.004423678,0.00001800949,0.00004149463,0.0001457231,0.00005037974,0.00129565,0.9841551,0.00006607668,0.005063025,0.000007754949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946228,0.003064252,0.0006300736,0.0001455636,0.0001067379,0.00003185548,0.0002398285,0.000087762,0.00107117],"genre_scores_gemma":[0.9954228,0.001463475,0.0006823289,0.00008226272,0.00002129332,0.00004233908,0.0004785023,0.00001245269,0.001794504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00120941,"threshold_uncertainty_score":0.004045844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04211903040655583,"score_gpt":0.2449900919705408,"score_spread":0.202871061563985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}