{"id":"W4309928804","doi":"10.1016/j.virs.2022.11.006","title":"OGG1 inhibition suppresses African swine fever virus replication","year":2022,"lang":"en","type":"article","venue":"Virologica Sinica","topic":"Animal Disease Management and Epidemiology","field":"Agricultural and Biological Sciences","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Agricultural Science and Technology Innovation Program; Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences; National Key Research and Development Program of China; Chinese Academy of Agricultural Sciences; Natural Science Foundation of Gansu Province; Chinese Academy of Sciences; State Key Laboratory of Veterinary Etiological Biology; Institute of Genetics; National Natural Science Foundation of China","keywords":"African swine fever virus; Biology; DNA glycosylase; Viral replication; Virology; Base excision repair; Virus; DNA; DNA damage; Interferon; Reactive oxygen species; Molecular biology; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005737212,0.0001416677,0.0002097126,0.00001813885,0.000586524,0.00002562909,0.0003090897,0.00006629361,0.008062593],"category_scores_gemma":[0.0002190842,0.00006029114,0.0001275583,0.0003590556,0.00009432364,0.00009089486,0.0004693788,0.000178682,0.0001376834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003460545,"about_ca_system_score_gemma":0.000004388663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001570077,"about_ca_topic_score_gemma":0.00005318141,"domain_scores_codex":[0.9982498,0.0003623609,0.0002982912,0.0005788713,0.0001914483,0.0003192489],"domain_scores_gemma":[0.9992642,0.0002918082,0.000168495,0.0001632478,0.00002431732,0.00008793882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007099976,0.001024668,0.02120328,0.000008930587,0.0000555289,0.00004579445,0.00006964587,0.0001503684,0.7862003,0.008368814,0.1430053,0.03915741],"study_design_scores_gemma":[0.000125504,0.0006996167,0.5111173,0.000001184241,0.00002362509,0.000004616179,0.0001627448,0.0001100964,0.0003535607,0.003691931,0.4835266,0.0001831378],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777423,0.000165518,0.000006848566,0.01282306,0.00008360799,0.0002617436,0.0001174092,0.0002077195,0.008591782],"genre_scores_gemma":[0.9938669,0.00008822532,0.00004927828,0.004577912,0.0001888805,0.0001832832,0.0004249571,0.000001285244,0.0006192583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7858467,"threshold_uncertainty_score":0.9928442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04211903040655583,"score_gpt":0.2449900919705408,"score_spread":0.202871061563985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}