{"id":"W4309939018","doi":"10.1016/j.kint.2022.10.024","title":"Quantitative scoring of progression in transplant glomerulopathy using digital pathology may be superior to Banff cg scoring","year":2022,"lang":"en","type":"article","venue":"Kidney International","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Shire Human Genetic Therapies","keywords":"Medicine; Surrogate endpoint; Concordance; Receiver operating characteristic; Biopsy; Internal medicine; Glomerulopathy; Clinical endpoint; Pathological; Pathology; Radiology; Clinical trial; Urology; Kidney; Glomerulonephritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006429418,0.00100064,0.001040579,0.005775735,0.0005304703,0.002706391,0.0006324355,0.0008150999,0.004402095],"category_scores_gemma":[0.00870926,0.0003029286,0.0007548016,0.002249597,0.0006099078,0.002458339,0.0009601195,0.0007379266,0.0008419253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005507437,"about_ca_system_score_gemma":0.0004332452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002432911,"about_ca_topic_score_gemma":0.005171594,"domain_scores_codex":[0.9970776,0.001119657,0.0003842727,0.0003365357,0.0009106002,0.0001714106],"domain_scores_gemma":[0.9924394,0.002546482,0.001983378,0.0005669817,0.002068782,0.0003949388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001991041,0.000244342,0.7963703,0.0005989287,0.0005104613,0.0003527876,0.0001359787,0.001947494,0.01237452,0.001324284,0.002412626,0.1817372],"study_design_scores_gemma":[0.0001668061,0.001655696,0.9313639,0.0004589438,0.0008045601,0.003301525,0.0004073635,0.03432181,0.0140841,0.004390295,0.00884528,0.0001996389],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.87601,0.008651949,0.04917391,0.001041354,0.0006819663,0.0005363054,0.001978249,0.001874416,0.0600519],"genre_scores_gemma":[0.9692494,0.001153442,0.02611715,0.0002677709,0.0002494251,0.00006627062,0.0005870986,0.00008179678,0.002227613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006429418,"threshold_uncertainty_score":0.03400242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0456503783901828,"score_gpt":0.3598834295624445,"score_spread":0.3142330511722617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}