{"id":"W4309944801","doi":"10.1002/pld3.460","title":"An open source plant kinase chemogenomics set","year":2022,"lang":"en","type":"article","venue":"Plant Direct","topic":"Plant Reproductive Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo; Foundation for Food and Agriculture Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Pew Charitable Trusts","keywords":"Arabidopsis; Kinase; Biology; Protein-Serine-Threonine Kinases; Biochemistry; Oryza sativa; Kinome; Protein kinase A; Cell biology; Gene; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004674376,0.0001766477,0.0002103257,0.00004220384,0.0002334874,0.00003633232,0.0008205172,0.00007288835,0.0001002078],"category_scores_gemma":[0.00005384058,0.0001753596,0.00004273504,0.00006809547,0.00004487267,0.000004623976,0.0007962381,0.0001374769,0.00001584045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003903982,"about_ca_system_score_gemma":0.0001006642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001787297,"about_ca_topic_score_gemma":0.00007475804,"domain_scores_codex":[0.9985065,0.0002115935,0.0001628964,0.0006977663,0.0001067526,0.0003145315],"domain_scores_gemma":[0.9991779,0.0000200079,0.00009229626,0.0005896164,0.00001931215,0.0001008302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006073441,0.0001410894,0.003786218,0.000005204663,0.00007058134,0.00005282672,0.00008056594,0.0003075766,0.9701661,0.00004737958,0.02395064,0.0007845058],"study_design_scores_gemma":[0.0003429291,0.0005113305,0.0009627976,0.000001846771,0.00001495158,0.0004658343,0.00009675669,0.0001394258,0.2681741,0.00001844085,0.728988,0.0002836425],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900083,0.0004182061,0.00003206484,0.0001131758,0.0003062797,0.0003317851,0.005138801,0.00003851434,0.003612851],"genre_scores_gemma":[0.9844247,0.00007360535,0.0002696122,0.0006503804,0.0003194589,0.0001107154,0.01279265,0.00003424826,0.001324673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7050373,"threshold_uncertainty_score":0.7150955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01990338988709907,"score_gpt":0.2525176582648995,"score_spread":0.2326142683778004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}