{"id":"W4310089938","doi":"10.1182/blood-2022-165775","title":"Phase I Study Evaluating Outcomes of Autologous HIV-Specific T Cells Targeting Non-Escaped Epitopes (HST-NEET) Therapy in HIV+ Individuals on ART (NCT03485963)","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"","keywords":"Epitope; Medicine; Immunology; Adverse effect; Virology; Antibody; Immune system; Viral load; CD8; Internal medicine; Human immunodeficiency virus (HIV)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001559998,0.000893098,0.001152696,0.0002585516,0.0003916468,0.0007122804,0.0006474492,0.001502411,0.005137144],"category_scores_gemma":[0.0007221234,0.0003760983,0.0008905038,0.0002289175,0.00074274,0.0005345853,0.0002628203,0.00223036,0.000831584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005509476,"about_ca_system_score_gemma":0.00133595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000719938,"about_ca_topic_score_gemma":0.001454623,"domain_scores_codex":[0.9996173,0.0001950888,0.00001742526,0.00005283994,0.00003601798,0.0000812814],"domain_scores_gemma":[0.9993632,0.0001262402,0.000144974,0.00004841544,0.00005510508,0.0002619177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7652502,0.1082848,0.00926754,0.00053742,0.0006341094,0.000265311,0.0002686994,0.00190733,0.05308407,0.0003315214,0.00238177,0.05778722],"study_design_scores_gemma":[0.181066,0.807386,0.005962759,0.00002316455,0.000152578,0.00010148,0.00004385354,0.0004277453,0.003542964,0.0001441731,0.001140121,0.000009187312],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990752,0.0005786002,0.0003887649,0.0001858622,0.00007520169,0.004453195,0.00130011,0.00005403459,0.002212085],"genre_scores_gemma":[0.9854725,0.0006243791,0.00129504,0.0006318277,0.0001084686,0.005478973,0.001991455,0.00001889516,0.004378407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005137144,"threshold_uncertainty_score":0.01718545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03200124366610448,"score_gpt":0.3233416515998108,"score_spread":0.2913404079337063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}