{"id":"W4310092952","doi":"10.1182/blood-2022-157256","title":"Analysis of Immune Pharmacodynamic and Baseline Biomarkers in Patients with Relapsed or Refractory Follicular Lymphoma Treated with Mosunetuzumab in Combination with Lenalidomide","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"","keywords":"Medicine; Lenalidomide; Follicular lymphoma; Internal medicine; Lymphoma; Gastroenterology; Pharmacodynamics; CD20; Rituximab; Oncology; Immunology; Pharmacokinetics; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005044073,0.0002726795,0.0006794313,0.000342146,0.0002248968,0.0005167991,0.0002200408,0.0003816457,0.0008081633],"category_scores_gemma":[0.000836433,0.0001459227,0.0003068366,0.0003689053,0.0001633341,0.0002341544,0.0001620956,0.0004856983,0.0002070542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005199765,"about_ca_system_score_gemma":0.0002749751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005952782,"about_ca_topic_score_gemma":0.0008947231,"domain_scores_codex":[0.9997403,0.00007896176,0.00002468044,0.00006344719,0.00004936764,0.00004323975],"domain_scores_gemma":[0.9995548,0.00009329695,0.0001445122,0.00002123548,0.00003996082,0.0001461954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0543018,0.001965961,0.867771,0.0001694849,0.0005794341,0.001064549,0.0002447876,0.000914033,0.02590953,0.00006674555,0.001016964,0.04599572],"study_design_scores_gemma":[0.001665,0.01869267,0.9717713,0.00002196244,0.0003808195,0.00152826,0.0001377634,0.001633466,0.002255254,0.00006871621,0.001829673,0.00001516324],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998723,0.0005161674,0.0000603422,0.00003953354,0.000005278579,0.00004058047,0.0001556641,0.000007298722,0.0004522043],"genre_scores_gemma":[0.9993324,0.00008051038,0.0000787198,0.00006423606,0.00001362183,0.00003059643,0.0002582351,0.000001493406,0.0001403739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008081633,"threshold_uncertainty_score":0.003772736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005207669908985609,"score_gpt":0.2180618201127861,"score_spread":0.2128541502038005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}