{"id":"W4310103232","doi":"10.1182/blood-2022-169307","title":"Umbrella Trial in Myeloid Malignancies: The Myelomatch National Clinical Trials Network Precision Medicine Initiative","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Clinical trial; Medicine; Precision medicine; Oncology; Internal medicine; Intensive care medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03954251,0.0008170872,0.001571147,0.0008787952,0.0007953365,0.003434988,0.00142325,0.001801157,0.01792642],"category_scores_gemma":[0.01769988,0.0004526512,0.001164929,0.002118234,0.0007166086,0.001744149,0.001774292,0.003944755,0.006278158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002324481,"about_ca_system_score_gemma":0.003847848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009498459,"about_ca_topic_score_gemma":0.003343881,"domain_scores_codex":[0.9839553,0.01080559,0.0008097612,0.001444512,0.00257203,0.0004126377],"domain_scores_gemma":[0.9875391,0.004314974,0.002607058,0.001459369,0.0015313,0.002548121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.04232938,0.001005166,0.01036414,0.002710145,0.001463914,0.0000685244,0.0001225993,0.001706606,0.002086052,0.009931848,0.4570925,0.4711191],"study_design_scores_gemma":[0.1208307,0.01595884,0.07857262,0.006958654,0.002136943,0.0004766666,0.00009831639,0.006791456,0.002622443,0.0197123,0.7456514,0.0001896953],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.09715288,0.1814343,0.03240944,0.2342341,0.009142916,0.0274359,0.1110781,0.005123022,0.3019893],"genre_scores_gemma":[0.3650089,0.06208833,0.1489206,0.1499984,0.01946812,0.05222977,0.1307265,0.001482624,0.07007676],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03954251,"threshold_uncertainty_score":0.2091233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2014546901535358,"score_gpt":0.4464099948078948,"score_spread":0.244955304654359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}