{"id":"W4310127708","doi":"10.1182/blood-2022-159594","title":"Mosunetuzumab with Polatuzumab Vedotin Is Effective and Has a Manageable Safety Profile in Patients Aged <65 and ≥65 Years with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL) and ≥1 Prior Therapy: Subgroup Analysis of a Phase Ib/II Study","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; Saskatchewan Cancer Agency","funders":"","keywords":"Diffuse large B-cell lymphoma; Medicine; Internal medicine; Lymphoma; Oncology; Refractory (planetary science); Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001418296,0.0004678843,0.001277386,0.0003974597,0.0002472484,0.000884418,0.000332519,0.0003941835,0.001249053],"category_scores_gemma":[0.001354363,0.0002390164,0.002647571,0.0005603715,0.0002774645,0.0004904734,0.0002962996,0.0007295242,0.0001636963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005558891,"about_ca_system_score_gemma":0.0005421606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005284174,"about_ca_topic_score_gemma":0.002022655,"domain_scores_codex":[0.9993232,0.0002369709,0.0001072219,0.000134845,0.0001047664,0.00009304771],"domain_scores_gemma":[0.9994356,0.0001322694,0.0001862564,0.00007347466,0.00003781848,0.000134673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5023733,0.004527665,0.2919505,0.0009208489,0.01872255,0.0005416345,0.000422742,0.001762865,0.03594718,0.0001427301,0.001928529,0.1407596],"study_design_scores_gemma":[0.1076992,0.13123,0.7206507,0.0001591747,0.01976714,0.002064055,0.0004303404,0.00316928,0.007396516,0.0004508705,0.00689509,0.00008758677],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965472,0.002338775,0.0001517291,0.00008166737,0.00001716471,0.0001734604,0.0002705632,0.000008628257,0.0004108809],"genre_scores_gemma":[0.9982091,0.0005928454,0.0002209412,0.0001407169,0.00003352451,0.0001304129,0.0004725821,0.000004407005,0.0001953847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001418296,"threshold_uncertainty_score":0.007500708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007074890573360376,"score_gpt":0.2245526384526863,"score_spread":0.2174777478793259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}