{"id":"W4310159176","doi":"10.1182/blood-2022-168998","title":"Immunophenotypic Switch in Leukemic Clone Is Very Common at the Time of Post-Transplant Relapse of Acute Myeloid Leukemia While Immunophenotypic Profile at Diagnosis Correlates with Adverse Outcomes after Post-Transplant Relapse","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Myeloid leukemia; clone (Java method); Immunophenotyping; Leukemia; Adverse effect; Myeloid; Oncology; Internal medicine; Immunology; Cancer research; Flow cytometry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002812379,0.0001593626,0.0002717175,0.0005634564,0.0002950364,0.0006671348,0.0002888751,0.0003771015,0.003360949],"category_scores_gemma":[0.001530435,0.00008577746,0.0001894947,0.0005325701,0.0002371848,0.0004568388,0.000322881,0.0006558576,0.0005529712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002029415,"about_ca_system_score_gemma":0.000184715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002934464,"about_ca_topic_score_gemma":0.0004202911,"domain_scores_codex":[0.999617,0.00006238332,0.00003885345,0.00006982524,0.00008792678,0.0001239587],"domain_scores_gemma":[0.9984661,0.0002745406,0.0007711302,0.0000834267,0.0001252242,0.0002795368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006451595,0.00005640162,0.9799157,0.00001913274,0.00003677628,0.0007444159,0.00007522794,0.00005885386,0.009857507,0.0001052294,0.0002300189,0.008255585],"study_design_scores_gemma":[0.000006348242,0.000211154,0.993093,0.00001083057,0.00002758756,0.003720893,0.0001589539,0.000143274,0.001770342,0.0001211333,0.0007309249,0.000005522701],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979913,0.0003390516,0.0001460815,0.00004731043,0.00001165515,0.00000733336,0.0001447208,0.00001042573,0.00130217],"genre_scores_gemma":[0.9993567,0.00009037781,0.00005686673,0.00003415462,0.00001821905,0.000004231742,0.000231915,0.00000313431,0.0002044598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003360949,"threshold_uncertainty_score":0.01124352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006132046537454842,"score_gpt":0.2196918573127505,"score_spread":0.2135598107752956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}