{"id":"W4310159202","doi":"10.1182/blood-2022-158492","title":"Association of Metabolic Tumor Volume (MTV) and Clinical Outcomes in Second-Line (2L) Relapsed/Refractory (R/R) Large B-Cell Lymphoma (LBCL) Following Axicabtagene Ciloleucel (Axi-Cel) Versus Standard-of-Care (SOC) Therapy in ZUMA-7","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Refractory (planetary science); Oncology; Lymphoma; Internal medicine; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003078813,0.0001601755,0.0003623658,0.0001692162,0.0001356286,0.0004875701,0.0002011259,0.000294039,0.001821598],"category_scores_gemma":[0.0005243049,0.00007655835,0.0003574205,0.0001703392,0.0001519561,0.0003271745,0.0002139987,0.0005957516,0.0002154721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003098143,"about_ca_system_score_gemma":0.000237426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004771504,"about_ca_topic_score_gemma":0.0008372368,"domain_scores_codex":[0.9998678,0.00003299365,0.000008304571,0.00002913779,0.00001494732,0.00004675384],"domain_scores_gemma":[0.9996349,0.00006311072,0.00009310585,0.00001798437,0.00001578734,0.0001752826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1719582,0.004093575,0.738092,0.0001515353,0.0009252622,0.0004068575,0.0001467679,0.0008271146,0.008703767,0.0002026746,0.001595985,0.07289632],"study_design_scores_gemma":[0.002555551,0.03728057,0.9536352,0.00003442883,0.000734608,0.0004823921,0.0002219493,0.001869267,0.001337557,0.0002362019,0.001590395,0.00002202762],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990872,0.0004054554,0.0000246662,0.00004932735,0.00001219332,0.000006724522,0.00009498216,0.000003303787,0.0003160452],"genre_scores_gemma":[0.9992328,0.0001045462,0.00001699842,0.00003990899,0.00001998364,0.00001071421,0.0002636756,0.000001012468,0.000310373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001821598,"threshold_uncertainty_score":0.00609386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02600978317324755,"score_gpt":0.3245871880200717,"score_spread":0.2985774048468242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}