{"id":"W4310422504","doi":"10.1016/j.freeradbiomed.2022.11.036","title":"WITHDRAWN: Mitochondria need their sleep: Sleep-wake cycling and the role of redox, bioenergetics, and temperature regulation, involving cysteine-mediated redox signaling, uncoupling proteins, and substrate cycles","year":2022,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":true,"has_abstract":false,"ca_institutions":"McGill University; Canadian Nuclear Laboratories; McGill University Health Centre","funders":"","keywords":"Bioenergetics; Redox; Oxidative phosphorylation; Chemistry; Mitochondrion; Sleep (system call); Cell biology; Substrate (aquarium); Cysteine; Biochemistry; Biology; Computer science; Ecology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007232736,0.0004141481,0.0003702152,0.0003323722,0.000837421,0.001568552,0.0007235932,0.002697751,0.02093939],"category_scores_gemma":[0.003883956,0.0001577941,0.0003552933,0.0003890879,0.000910648,0.0009958104,0.0005187935,0.004169726,0.003629642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006564485,"about_ca_system_score_gemma":0.00155501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002432798,"about_ca_topic_score_gemma":0.006548208,"domain_scores_codex":[0.9997104,0.00005076606,0.0000383939,0.0000423377,0.0001191428,0.00003896491],"domain_scores_gemma":[0.9983698,0.0005552639,0.0001806442,0.0001178137,0.0004345915,0.0003419166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00588538,0.0003406686,0.009939691,0.0009571682,0.0002186683,0.004692876,0.001328535,0.0003137119,0.06774406,0.03099302,0.7130836,0.1645026],"study_design_scores_gemma":[0.000901044,0.0008845386,0.04925474,0.0004437615,0.0002246203,0.00654308,0.003064522,0.001022989,0.02756955,0.0617385,0.8481722,0.0001804013],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.07963661,0.01109795,0.004946921,0.7620188,0.1031806,0.0001470765,0.003965788,0.0009062673,0.03409989],"genre_scores_gemma":[0.5204009,0.01232625,0.005328902,0.2532026,0.03593332,0.0001728109,0.002588944,0.0002816836,0.1697646],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02093939,"threshold_uncertainty_score":0.07004923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003611899980361519,"score_gpt":0.2099207050134638,"score_spread":0.2063088050331023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}