{"id":"W4310465101","doi":"10.1161/circresaha.122.322003","title":"Maintenance of Enteral ACE2 Prevents Diabetic Retinopathy in Type 1 Diabetes","year":2022,"lang":"en","type":"article","venue":"Circulation Research","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Center for Research Resources; National Eye Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Endocrinology; Internal medicine; Angiotensin-converting enzyme 2; Medicine; Intestinal permeability; Diabetes mellitus; Glucose homeostasis; Enteral administration; Immunology; Biology; Insulin resistance; Parenteral nutrition; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002446334,0.0003645986,0.000364469,0.0001918807,0.0001372282,0.0003341238,0.0002236655,0.0002234794,0.001522915],"category_scores_gemma":[0.0001561111,0.000104008,0.0002393872,0.0001308849,0.0001793432,0.0001925301,0.0001875658,0.0007193208,0.0003133107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001688135,"about_ca_system_score_gemma":0.0001876904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002973325,"about_ca_topic_score_gemma":0.0006077847,"domain_scores_codex":[0.9998958,0.00001779404,0.000008897798,0.00002612217,0.0000241804,0.0000271817],"domain_scores_gemma":[0.9998341,0.00001067983,0.00005467051,0.00001740023,0.00001638281,0.0000667838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00357901,0.0007554231,0.002958796,0.0001394559,0.00004452079,0.0001091524,0.00002296604,0.00008893825,0.9815714,0.0000785364,0.000222269,0.0104296],"study_design_scores_gemma":[0.0008594767,0.01169421,0.08840203,0.00006282395,0.0003370016,0.001503403,0.0001672003,0.001810773,0.8844758,0.0001915497,0.01047007,0.00002559865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953008,0.002146166,0.001219715,0.0001285648,0.00004599229,0.00002599679,0.0002787862,0.00009265868,0.0007612089],"genre_scores_gemma":[0.9935092,0.001447303,0.001943734,0.0001311558,0.00003667821,0.00006034045,0.0005625491,0.00003536106,0.002273435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001522915,"threshold_uncertainty_score":0.005094707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07409907516313106,"score_gpt":0.3683226133382373,"score_spread":0.2942235381751063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}