{"id":"W4310522631","doi":"10.1186/s12934-022-01978-z","title":"Using phosphoglucose isomerase-deficient (pgi1Δ) Saccharomyces cerevisiae to map the impact of sugar phosphate levels on d-glucose and d-xylose sensing","year":2022,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Vetenskapsrådet; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Lunds Universitet","keywords":"Glucose-6-phosphate isomerase; Xylose; Saccharomyces cerevisiae; Sugar; Biochemistry; Chemistry; Food science; Biology; Microbiology; Fermentation; Yeast; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001413321,0.0008938995,0.0003886655,0.0004064105,0.000149585,0.0004218593,0.0004948234,0.0004215253,0.0006617552],"category_scores_gemma":[0.0001386802,0.0002114458,0.000464431,0.0006564013,0.0002778134,0.0002503218,0.0004578581,0.0007392598,0.0003699503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003820625,"about_ca_system_score_gemma":0.0002132587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002186448,"about_ca_topic_score_gemma":0.001764972,"domain_scores_codex":[0.9997988,0.00001328776,0.00002633102,0.00007371033,0.00006235333,0.00002550788],"domain_scores_gemma":[0.9998196,0.00002659804,0.00007713387,0.00002214281,0.00002404962,0.00003055652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007956523,0.00002913045,0.0002979879,0.00004837856,0.000007016215,0.00004016603,0.00001373231,0.00005939903,0.9986773,0.00002604311,0.00001620907,0.0007050498],"study_design_scores_gemma":[0.00001094372,0.0002783128,0.008794393,0.00001216676,0.0000368243,0.0002509831,0.00008413987,0.0009728331,0.9882289,0.0000556702,0.001262059,0.00001268864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883049,0.0008440327,0.005923964,0.0001051515,0.00004029046,0.00008526554,0.003770084,0.0001734856,0.0007528499],"genre_scores_gemma":[0.9715574,0.001391079,0.0183336,0.0001147667,0.00001155582,0.0001417557,0.005899285,0.0001744966,0.002376186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002186448,"threshold_uncertainty_score":0.004347503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02766722485780529,"score_gpt":0.29221496616246,"score_spread":0.2645477413046546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}