{"id":"W4310529362","doi":"10.1371/journal.ppat.1010598","title":"Targeting Nup358/RanBP2 by a viral protein disrupts stress granule formation","year":2022,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Science and Engineering Research Board; Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Stress granule; Biology; Cell biology; Ubiquitin ligase; RNA; Ribonucleoprotein; Virology; RNA-binding protein; Viral replication; Virus; Molecular biology; Ubiquitin; Translation (biology); Messenger RNA; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001030926,0.0003202424,0.0002135151,0.000134587,0.0001820001,0.0002535733,0.000286748,0.0003019877,0.0007060681],"category_scores_gemma":[0.00006872661,0.0001711849,0.0002382192,0.0001059767,0.0002517761,0.0001532769,0.0002094978,0.0004872543,0.0002788856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003999845,"about_ca_system_score_gemma":0.0002140869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001220546,"about_ca_topic_score_gemma":0.001568058,"domain_scores_codex":[0.999872,0.00001495458,0.00001573401,0.00003671573,0.00003349451,0.00002716838],"domain_scores_gemma":[0.9999073,0.0000122638,0.00003137669,0.00001093649,0.000006143378,0.00003193509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003285253,0.000006675805,0.00002922436,0.00001029178,0.000001785118,0.00001570036,0.000004338415,0.00002346157,0.9996835,0.00003640598,0.00001032259,0.0001454211],"study_design_scores_gemma":[0.000008868108,0.0001148011,0.002147114,0.000002989311,0.000006060307,0.0001038218,0.00001282017,0.001128037,0.9954537,0.00002462095,0.0009934189,0.000003692845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955147,0.0007176487,0.002267534,0.00006266894,0.00002758687,0.00002531895,0.000413076,0.0001257047,0.0008457952],"genre_scores_gemma":[0.9951525,0.0003050325,0.0023273,0.00003132216,0.00000477699,0.00002638113,0.0004346609,0.00002918761,0.001688829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001220546,"threshold_uncertainty_score":0.00290215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0089313460827696,"score_gpt":0.2352877491059141,"score_spread":0.2263564030231445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}