{"id":"W4310529362","doi":"10.1371/journal.ppat.1010598","title":"Targeting Nup358/RanBP2 by a viral protein disrupts stress granule formation","year":2022,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Science and Engineering Research Board; Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Stress granule; Biology; Cell biology; Ubiquitin ligase; RNA; Ribonucleoprotein; Virology; RNA-binding protein; Viral replication; Virus; Molecular biology; Ubiquitin; Translation (biology); Messenger RNA; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001924008,0.0001181252,0.0001026486,0.00003721453,0.0003698046,0.00003264107,0.0002029719,0.00004672786,0.00008097842],"category_scores_gemma":[0.00007761818,0.0001188983,0.00007024195,0.00008854406,0.00002507277,0.000008336132,0.0002254687,0.0001560441,0.00001162711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003266665,"about_ca_system_score_gemma":0.00003442711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002218159,"about_ca_topic_score_gemma":0.000007270125,"domain_scores_codex":[0.99876,0.0001383231,0.0001770544,0.0002597699,0.0003051293,0.0003597545],"domain_scores_gemma":[0.999576,0.000005470499,0.00006641671,0.0002137408,0.00004388062,0.00009448916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006226671,0.0001178624,0.0006718646,0.00003171986,0.00001860278,0.0000114471,0.00008270455,0.00009946908,0.9957632,0.00001621693,0.002251357,0.0008733355],"study_design_scores_gemma":[0.0006411535,0.0005374262,0.00009462574,0.00001351945,0.0000123074,0.00001020044,0.0005448234,0.006723318,0.9829345,0.00004364556,0.008166817,0.0002776883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971491,0.0004277104,0.001043572,0.0001291323,0.00003148977,0.0004304825,0.0004688776,0.00002224748,0.0002973625],"genre_scores_gemma":[0.9964426,0.00002501367,0.000349326,0.00009529825,0.0001001441,0.0002909689,0.001135951,0.00002520354,0.001535504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01282868,"threshold_uncertainty_score":0.4848532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0089313460827696,"score_gpt":0.2352877491059141,"score_spread":0.2263564030231445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}