{"id":"W4310567835","doi":"10.3324/haematol.2022.282014","title":"Methotrexate, cytarabine, thiotepa and rituximab (MATRix) chemoimmunotherapy for primary central nervous system lymphoma: a Toronto experience","year":2022,"lang":"en","type":"letter","venue":"Haematologica","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; St. Michael's Hospital; University of Toronto","funders":"","keywords":"Primary central nervous system lymphoma; Rituximab; Chemoimmunotherapy; Cytarabine; Medicine; ThioTEPA; Methotrexate; Oncology; Central nervous system; Lymphoma; Internal medicine; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002039164,0.0008259732,0.002289738,0.0001007516,0.0004085491,0.0001010333,0.0003493383,0.0008264217,0.0005892296],"category_scores_gemma":[0.00005450911,0.0006287766,0.0006013738,0.0001376474,0.0001716585,0.0001165165,0.0001991405,0.0003674611,0.00001447306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002065113,"about_ca_system_score_gemma":0.0002775239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001136727,"about_ca_topic_score_gemma":0.00002199926,"domain_scores_codex":[0.9962406,0.000188019,0.0007823068,0.001199379,0.0005955138,0.0009942065],"domain_scores_gemma":[0.9977979,0.0005109964,0.0004525309,0.0009652901,0.000101271,0.0001719928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003574488,0.003429905,0.001517299,0.008788584,0.002257473,0.02373459,0.003302019,0.00000144328,0.0003078081,0.00111145,0.8268909,0.125084],"study_design_scores_gemma":[0.01259408,0.001451229,0.01654785,0.0005461736,0.0009119846,0.0110335,0.00100392,0.00007767582,0.0004596859,0.00004870232,0.9543697,0.0009555623],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.3898844,0.1855816,0.0005857074,0.3822217,0.00429205,0.01957483,0.001653866,0.002454567,0.01375133],"genre_scores_gemma":[0.2398173,0.01365077,0.03692297,0.663001,0.004046719,0.02691286,0.006546766,0.0009305879,0.008171058],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.2807794,"threshold_uncertainty_score":0.9996164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01846210685665928,"score_gpt":0.2796452937281932,"score_spread":0.261183186871534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}