{"id":"W4310567835","doi":"10.3324/haematol.2022.282014","title":"Methotrexate, cytarabine, thiotepa and rituximab (MATRix) chemoimmunotherapy for primary central nervous system lymphoma: a Toronto experience","year":2022,"lang":"en","type":"letter","venue":"Haematologica","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; Princess Margaret Cancer Centre; St. Michael's Hospital; University of Toronto","funders":"","keywords":"Primary central nervous system lymphoma; Rituximab; Chemoimmunotherapy; Cytarabine; Medicine; ThioTEPA; Methotrexate; Oncology; Central nervous system; Lymphoma; Internal medicine; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004493103,0.0004562604,0.0002956474,0.0002745931,0.001383614,0.0007440335,0.0006957243,0.002485428,0.002487379],"category_scores_gemma":[0.001644263,0.0002603371,0.0004290152,0.0009928822,0.0007493396,0.0005187364,0.0003732357,0.001228176,0.0006723388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005104439,"about_ca_system_score_gemma":0.002783834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.128866,"about_ca_topic_score_gemma":0.3325996,"domain_scores_codex":[0.9995717,0.0001206452,0.00005021255,0.0000309442,0.0001017713,0.0001247903],"domain_scores_gemma":[0.9990715,0.0003170077,0.0001265102,0.00004297837,0.0001331805,0.0003088629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.004740105,0.001080684,0.1380886,0.001171565,0.0004340379,0.4571918,0.006638782,0.003916002,0.009614629,0.003757595,0.2240238,0.1493425],"study_design_scores_gemma":[0.001356803,0.00342058,0.3530824,0.000781169,0.0006703975,0.3005368,0.00426888,0.002695208,0.003159892,0.001562349,0.3283221,0.0001433853],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.671701,0.06624072,0.0008217506,0.1390071,0.002349882,0.0001694613,0.001096933,0.00007058577,0.1185425],"genre_scores_gemma":[0.9120085,0.03178407,0.0007921685,0.01956958,0.002408857,0.00004868165,0.0007271147,0.00004268117,0.03261832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.128866,"threshold_uncertainty_score":0.2562317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01846210685665928,"score_gpt":0.2796452937281932,"score_spread":0.261183186871534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}