{"id":"W4310643040","doi":"10.7326/m22-3317","title":"Ongoing Need for Clinical Trials and Contemporary End Points for Outpatient COVID-19","year":2022,"lang":"en","type":"letter","venue":"Annals of Internal Medicine","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Clinical trial; Coronavirus disease 2019 (COVID-19); Family medicine; Clinical Practice; MEDLINE; Alternative medicine; Randomized controlled trial; Outpatient clinic; Gerontology; Infectious disease (medical specialty); Surgery; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.136913,0.001233309,0.005575069,0.004236247,0.003388025,0.01175226,0.00676371,0.03925445,0.01014383],"category_scores_gemma":[0.5032112,0.001765228,0.004748964,0.003900191,0.007817634,0.01819274,0.005225583,0.04811935,0.005740331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01005829,"about_ca_system_score_gemma":0.03001835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003281877,"about_ca_topic_score_gemma":0.008226153,"domain_scores_codex":[0.8492711,0.08645642,0.02928278,0.005389195,0.02675758,0.002843023],"domain_scores_gemma":[0.2267757,0.6378999,0.03082071,0.01304852,0.07188834,0.01956679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002905766,0.00005027841,0.0006383027,0.002887538,0.0002066477,0.0002689394,0.0001581957,0.00007702966,0.00008279988,0.005470667,0.943485,0.04638408],"study_design_scores_gemma":[0.001561308,0.0002946398,0.002012642,0.02432465,0.0008609652,0.001199726,0.0006859548,0.0009028403,0.0002916991,0.06289812,0.9047648,0.0002027194],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00009129287,0.01487779,0.0002621299,0.9585513,0.02544823,0.00002925535,0.0001011902,0.00002474011,0.0006139789],"genre_scores_gemma":[0.002613256,0.0149787,0.003180596,0.8425475,0.1356395,0.0002369947,0.0001554039,0.00005464343,0.0005934832],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.136913,"threshold_uncertainty_score":0.7240738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5978066682960983,"score_gpt":0.6121150980089674,"score_spread":0.01430842971286905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}