{"id":"W4310668156","doi":"10.1111/all.15609","title":"Sounding the alarmins—The role of alarmin cytokines in asthma","year":2022,"lang":"en","type":"review","venue":"Allergy","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta; University of Saskatchewan; Université Laval; Vancouver General Hospital; University of British Columbia; McMaster University","funders":"Sanofi Genzyme; Grifols; Covis Pharma; Sanofi; Regeneron Pharmaceuticals; AstraZeneca Canada; Teva Pharmaceutical Industries; Genentech; AstraZeneca; GlaxoSmithKline; Amgen","keywords":"Thymic stromal lymphopoietin; Immunology; Medicine; Asthma; Interleukin 13; Inflammation; Bronchoconstriction; Pathophysiology of asthma; Cytokine; Interleukin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006947983,0.000387625,0.001129475,0.0001770975,0.0003256318,0.00001331888,0.001064662,0.0003904299,0.00101621],"category_scores_gemma":[0.000163406,0.0002221721,0.0004457302,0.0004427412,0.0002457603,0.00004181568,0.0004330716,0.0009496373,0.0001920735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007238119,"about_ca_system_score_gemma":0.0003047388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003532351,"about_ca_topic_score_gemma":0.000314894,"domain_scores_codex":[0.9973962,0.0009834563,0.0006883774,0.000385718,0.00007302927,0.0004732275],"domain_scores_gemma":[0.9980413,0.0007926389,0.0004361444,0.0006895209,0.00002737838,0.00001304707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002119747,0.000122898,0.000006972298,0.0006821784,0.0007702935,0.00001691368,0.00115393,0.000002405992,0.0002656175,0.006466679,0.002534202,0.9879567],"study_design_scores_gemma":[0.0002161306,0.0000744245,0.000008276291,0.0005139895,0.00008905435,0.0001798156,0.0005445558,4.029176e-7,0.00008146086,0.00022217,0.997839,0.0002307066],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001051458,0.9910433,0.000002542406,0.00003055177,0.001032698,0.0004307438,0.0008390713,0.0000269884,0.006488926],"genre_scores_gemma":[0.000440216,0.996431,0.000006968187,0.00007499618,0.000113164,0.0002311696,0.000514149,0.00005017031,0.002138182],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9953048,"threshold_uncertainty_score":0.999897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03171513119635824,"score_gpt":0.269298654756722,"score_spread":0.2375835235603638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}