{"id":"W4310699919","doi":"10.1038/s41597-022-01837-x","title":"Mechanical Unloading of Engineered Human Meniscus Models Under Simulated Microgravity: A Transcriptomic Study","year":2022,"lang":"en","type":"article","venue":"Scientific Data","topic":"Spaceflight effects on biology","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; University of British Columbia; Canada Foundation for Innovation; Government of Canada; Canadian Institutes of Health Research; Alberta Cancer Foundation; Alberta Innovates - Health Solutions; Women and Children's Health Research Institute","keywords":"Meniscus; Transcriptome; Computer science; Computational biology; Biology; Physics; Optics; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002682797,0.0001969026,0.0001982186,0.0002652847,0.0002140942,0.0002660088,0.0001150297,0.0002143557,0.0006301884],"category_scores_gemma":[0.0001558341,0.00008787394,0.000337249,0.000216799,0.0001925628,0.0001364659,0.0001828339,0.0002596084,0.0001726973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001213382,"about_ca_system_score_gemma":0.0001574882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007180783,"about_ca_topic_score_gemma":0.001143833,"domain_scores_codex":[0.9998522,0.00001718036,0.00001377662,0.00004126176,0.00005129573,0.00002432483],"domain_scores_gemma":[0.9998845,0.00002371319,0.00003230035,0.00001712889,0.00002654579,0.00001582789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001086277,0.00002929366,0.0005867813,0.00004595553,0.000008300693,0.0000556891,0.00005306866,0.00009175976,0.9979361,0.00003383753,0.0000234054,0.001027181],"study_design_scores_gemma":[0.00003695151,0.001828941,0.07515577,0.00003443459,0.0001506215,0.0008256864,0.0006005793,0.003550801,0.9128476,0.0001199561,0.00481685,0.00003178713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941929,0.0007600191,0.003590483,0.0000316935,0.00002481514,0.00004753223,0.0008726377,0.00002155295,0.0004583884],"genre_scores_gemma":[0.9896361,0.001014274,0.005035657,0.00009860297,0.00001400264,0.0001744538,0.002260682,0.00001967108,0.001746538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007180783,"threshold_uncertainty_score":0.002108216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1043738739157414,"score_gpt":0.3480758117944599,"score_spread":0.2437019378787185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}