{"id":"W4310785106","doi":"10.1038/s41541-022-00574-x","title":"Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis","year":2022,"lang":"en","type":"article","venue":"npj Vaccines","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill Genome Centre; McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Global Health Innovative Technology Fund","keywords":"Leishmania donovani; Visceral leishmaniasis; Leishmaniasis; Immunology; Leishmania mexicana; Immunization; Disease; Biology; Medicine; Leishmania; Virology; Immune system; Parasite hosting; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006618232,0.0004196363,0.0007023125,0.0007908893,0.00103939,0.00009558075,0.0003757613,0.00006414733,0.001920254],"category_scores_gemma":[0.0002763063,0.0003885883,0.0003803018,0.001417421,0.00007764322,0.0001782271,0.0006025299,0.0009012992,0.0001376056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009058752,"about_ca_system_score_gemma":0.0002313351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000778263,"about_ca_topic_score_gemma":0.0006592479,"domain_scores_codex":[0.9960307,0.0002424419,0.0006112721,0.0008324544,0.001327355,0.0009557723],"domain_scores_gemma":[0.9982767,0.00008956659,0.0002104813,0.0007326346,0.000360581,0.0003300068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005139314,0.004298376,0.3874891,0.001162946,0.002618869,0.001527325,0.003259357,0.001987944,0.05338412,0.006140503,0.4201427,0.1128495],"study_design_scores_gemma":[0.01206136,0.003595721,0.4033144,0.000239604,0.0005412464,0.0004387611,0.005983336,0.003545499,0.01629073,0.0003630071,0.5520003,0.001626003],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9527531,0.0008631133,0.00005456672,0.01304234,0.000828002,0.002338059,0.00004889554,0.0004476071,0.02962437],"genre_scores_gemma":[0.9722741,0.0001667748,0.0001454673,0.001598114,0.0004945087,0.0007717292,0.00006058489,0.00009158299,0.02439711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1318577,"threshold_uncertainty_score":0.9998566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03385937387554869,"score_gpt":0.2824335031093909,"score_spread":0.2485741292338422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}