{"id":"W4310785106","doi":"10.1038/s41541-022-00574-x","title":"Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis","year":2022,"lang":"en","type":"article","venue":"npj Vaccines","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill Genome Centre; McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Global Health Innovative Technology Fund","keywords":"Leishmania donovani; Visceral leishmaniasis; Leishmaniasis; Immunology; Leishmania mexicana; Immunization; Disease; Biology; Medicine; Leishmania; Virology; Immune system; Parasite hosting; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009556689,0.0002600771,0.0001782096,0.0001894443,0.0001262747,0.0002909886,0.0001942104,0.000313005,0.001753622],"category_scores_gemma":[0.00007876124,0.0001046782,0.000141973,0.00007842892,0.0002115119,0.0001341194,0.000145869,0.0005315905,0.000275615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002469933,"about_ca_system_score_gemma":0.0001099659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006488492,"about_ca_topic_score_gemma":0.0007499261,"domain_scores_codex":[0.9999269,0.00001178023,0.000006324597,0.0000185627,0.00001672876,0.00001970547],"domain_scores_gemma":[0.9999168,0.000009063943,0.00002782112,0.000009118799,0.00001028674,0.00002702099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002029474,0.00005182505,0.000220274,0.00005040302,0.000007292876,0.00003935234,0.00001180277,0.00005230275,0.9983694,0.00007131479,0.00009744137,0.0008257471],"study_design_scores_gemma":[0.0001125364,0.001618226,0.01655436,0.00003139499,0.00007047845,0.0005980821,0.0001564471,0.001748822,0.9657291,0.00009956227,0.01326481,0.00001613713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996338,0.0006302733,0.0009892061,0.0001668721,0.00004120914,0.00002609977,0.000527125,0.00007492882,0.001206291],"genre_scores_gemma":[0.995007,0.0003298725,0.0006005837,0.00007084594,0.000006322245,0.00002581795,0.0006203697,0.00001559347,0.003323689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001753622,"threshold_uncertainty_score":0.005866468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03385937387554869,"score_gpt":0.2824335031093909,"score_spread":0.2485741292338422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}