{"id":"W4310957110","doi":"10.1007/s11096-022-01509-1","title":"Comparative efficacy of advanced treatments in biologic-naïve or biologic-experienced patients with ulcerative colitis: a systematic review and network meta-analysis","year":2022,"lang":"en","type":"review","venue":"International Journal of Clinical Pharmacy","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Galápagos; Gilead Sciences","keywords":"Medicine; Ulcerative colitis; Pharmacy; Meta-analysis; Internal medicine; Biologic Agents; Intensive care medicine; Family medicine; Rheumatoid arthritis; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02584127,0.002619812,0.01922618,0.008431555,0.0005090944,0.003186325,0.002210306,0.002050443,0.003005959],"category_scores_gemma":[0.0540182,0.001365002,0.0380123,0.007736695,0.0008363816,0.001976623,0.001751868,0.001797966,0.0002364003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003042457,"about_ca_system_score_gemma":0.002516797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005469959,"about_ca_topic_score_gemma":0.009019192,"domain_scores_codex":[0.9742503,0.01671376,0.004685823,0.002116557,0.001869516,0.0003640592],"domain_scores_gemma":[0.9523711,0.03860157,0.005979083,0.001053781,0.001632571,0.0003619199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002583591,0.00002451335,0.003677465,0.1765795,0.8080705,0.0000701531,0.00005534208,0.0008371967,0.0001058227,0.0001439852,0.0002779216,0.007573807],"study_design_scores_gemma":[0.00080358,0.0001656388,0.002563702,0.01118399,0.9838832,0.00005510111,0.00002669063,0.0003398868,0.00005825046,0.0002376373,0.0006648026,0.00001750239],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00912678,0.9879251,0.001118629,0.0002399574,0.0001479725,0.0004135731,0.0006918537,0.00002570293,0.0003104287],"genre_scores_gemma":[0.3981834,0.5922559,0.004544845,0.0009098637,0.0002945992,0.002135423,0.001338489,0.00004094272,0.000296443],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02584127,"threshold_uncertainty_score":0.1366633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1963214552039663,"score_gpt":0.5016591030533896,"score_spread":0.3053376478494232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}