{"id":"W4311021004","doi":"10.1111/ctr.14851","title":"Restriction of interleukin‐6 alters endothelial cell immunogenicity in an allogenic environment","year":2022,"lang":"en","type":"article","venue":"Clinical Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"ViTRAK Systems (Canada)","funders":"","keywords":"Endothelial stem cell; Immunology; Immunogenicity; Antibody; Medicine; Endothelium; Endothelial activation; T cell; Blockade; Inflammation; Immune system; Cell biology; Biology; In vitro; Receptor; Endocrinology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003524374,0.0001130277,0.0002900601,0.0001667798,0.00007181279,0.000006114917,0.00008611348,0.00005908506,0.0003114949],"category_scores_gemma":[0.000004995161,0.0001120073,0.0001971131,0.0001320847,0.0000619696,0.00008385071,0.000008702174,0.0002589018,0.00001274149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001150424,"about_ca_system_score_gemma":0.00005734752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002288034,"about_ca_topic_score_gemma":0.00004223885,"domain_scores_codex":[0.9982485,0.0002732037,0.0007598595,0.0002825338,0.000290034,0.0001459226],"domain_scores_gemma":[0.9993861,0.0001682395,0.000161274,0.0001893625,0.0000136117,0.00008135223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01116973,0.004319192,0.8920499,0.0004269986,0.0002019759,0.0004496716,0.001538567,0.003549059,0.07916984,0.0001712726,0.000006289874,0.006947506],"study_design_scores_gemma":[0.01373976,0.003589132,0.9637209,0.0000825073,0.0004599513,0.00009459529,0.0002617315,0.0004763156,0.01699707,0.0001392938,0.0002557042,0.0001831141],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976013,0.00006671301,0.001025576,0.00006453128,0.0002238309,0.0004022532,0.0001980272,0.00001920348,0.00039853],"genre_scores_gemma":[0.9955577,0.002419873,0.001051559,0.0001306663,0.00003192,0.00004989038,0.0006534559,0.00001529489,0.00008964345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07167093,"threshold_uncertainty_score":0.4567525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05112663619234265,"score_gpt":0.3459978689447418,"score_spread":0.2948712327523991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}