{"id":"W4311021004","doi":"10.1111/ctr.14851","title":"Restriction of interleukin‐6 alters endothelial cell immunogenicity in an allogenic environment","year":2022,"lang":"en","type":"article","venue":"Clinical Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"ViTRAK Systems (Canada)","funders":"","keywords":"Endothelial stem cell; Immunology; Immunogenicity; Antibody; Medicine; Endothelium; Endothelial activation; T cell; Blockade; Inflammation; Immune system; Cell biology; Biology; In vitro; Receptor; Endocrinology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001326699,0.0001750699,0.0001439738,0.0000852654,0.00005732147,0.0002505279,0.000100129,0.0001548342,0.001621171],"category_scores_gemma":[0.00008689897,0.00006881725,0.000131395,0.00006327414,0.0001045165,0.0001073258,0.00008139667,0.0005612369,0.0002343386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009371372,"about_ca_system_score_gemma":0.00007532739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001335311,"about_ca_topic_score_gemma":0.0001696827,"domain_scores_codex":[0.9998529,0.00005115541,0.00001207076,0.00001922969,0.00002396065,0.00004074468],"domain_scores_gemma":[0.9998986,0.00002649184,0.00002333388,0.00001703799,0.0000106848,0.00002381249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002861662,0.0001016008,0.0001377673,0.0000183572,0.000003553829,0.00001856359,0.000007018387,0.00004893322,0.9988855,0.00004013638,0.00001454102,0.0004379858],"study_design_scores_gemma":[0.00004365153,0.002412359,0.004693996,0.000007095753,0.00002506756,0.0001732779,0.00002802934,0.0008966781,0.9903841,0.00004183767,0.001290718,0.00000323573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983725,0.0004487348,0.0006413159,0.00002100524,0.00002276695,0.000007684778,0.00006272866,0.00001050943,0.0004127563],"genre_scores_gemma":[0.9985285,0.000227553,0.000421827,0.00003115762,0.000009058102,0.00001113004,0.0001000478,0.000003477099,0.0006672631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001621171,"threshold_uncertainty_score":0.005423307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05112663619234265,"score_gpt":0.3459978689447418,"score_spread":0.2948712327523991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}