{"id":"W4311024711","doi":"10.1056/nejmoa2209254","title":"Trial of Deferiprone in Parkinson’s Disease","year":2022,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":223,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Inserm Transfert; Medical Research Council; Centre hospitalier régional universitaire de Lille; Institut National de la Santé et de la Recherche Médicale","keywords":"Deferiprone; Parkinson's disease; Medicine; Disease; Internal medicine; Thalassemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001755847,0.0007748839,0.001658577,0.0002238091,0.0003971383,0.0005672413,0.0004761025,0.001476887,0.003053253],"category_scores_gemma":[0.001346642,0.0002541949,0.0008190415,0.0001895563,0.0004823538,0.0003940892,0.0002302333,0.001372292,0.00046033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004754328,"about_ca_system_score_gemma":0.0008206485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000445539,"about_ca_topic_score_gemma":0.0008128444,"domain_scores_codex":[0.9995061,0.0002744543,0.00003980806,0.00008083307,0.00003978999,0.00005900162],"domain_scores_gemma":[0.999126,0.000316963,0.0001624458,0.0000436236,0.00008992428,0.0002609829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9532244,0.00242724,0.001472898,0.001241712,0.0006175932,0.0001339095,0.00009127663,0.0003103386,0.004262657,0.0001690848,0.00115967,0.03488931],"study_design_scores_gemma":[0.8741081,0.1180628,0.003396863,0.0001024928,0.000280291,0.0001218243,0.00001968647,0.0002619276,0.0007210693,0.0001415947,0.002773302,0.000009924887],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9701307,0.02091441,0.0005725318,0.00170066,0.0008757006,0.002181155,0.0008517453,0.00007407752,0.002698921],"genre_scores_gemma":[0.9889392,0.003854997,0.0006643609,0.001153947,0.0004747487,0.002138767,0.0006802251,0.000007129336,0.002086693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003053253,"threshold_uncertainty_score":0.01021415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02506333049655647,"score_gpt":0.283375348103545,"score_spread":0.2583120176069886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}