{"id":"W4311039790","doi":"10.3390/cells11233828","title":"Extracellular Vesicles from Ocular Melanoma Have Pro-Fibrotic and Pro-Angiogenic Properties on the Tumor Microenvironment","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; University of California, San Diego; Canada Foundation for Innovation; Fondation des Maladies de l'Oeil; Fonds de Recherche du Québec - Santé; Thomas Jefferson University; Fondation CHU de Québec; Université Laval","keywords":"Hepatic stellate cell; Cell biology; Extracellular matrix; Tumor microenvironment; Biology; Flow cytometry; Angiogenesis; Chemistry; Immune system; Pathology; Cancer research; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007310369,0.0001829569,0.0001274252,0.0001199847,0.0001620664,0.0002562245,0.00003716338,0.0001862659,0.0005385811],"category_scores_gemma":[0.00008176573,0.00005411466,0.0001987824,0.00007746368,0.0001019501,0.0002173168,0.0002023315,0.0001909344,0.0001602699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001417444,"about_ca_system_score_gemma":0.00009042049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003105646,"about_ca_topic_score_gemma":0.0004561813,"domain_scores_codex":[0.9999375,0.00001394376,0.000004756851,0.000009753529,0.00001557042,0.00001834852],"domain_scores_gemma":[0.9999659,0.000006937571,0.000008994501,0.000005178997,0.000005899306,0.000007138065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003295009,0.000003584209,0.000292916,0.00001913166,0.000002747668,0.00007437439,0.00001465667,0.00003532643,0.998287,0.00009320554,0.00001195412,0.00113209],"study_design_scores_gemma":[0.000007330741,0.0001859498,0.01724094,0.00001346289,0.00002039176,0.0007651316,0.00009888029,0.0007228503,0.9771453,0.00009801307,0.003696051,0.000005605365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951256,0.001563247,0.001789744,0.00004783474,0.00001180856,0.0000109342,0.0001082554,0.00001642709,0.001326054],"genre_scores_gemma":[0.9972653,0.0006736832,0.0007311228,0.0000234846,0.000004852591,0.000008593204,0.0001464126,0.00000780545,0.001138795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005385811,"threshold_uncertainty_score":0.001801729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305440500532071,"score_gpt":0.1910489515529513,"score_spread":0.1779945465476306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}