{"id":"W4311039875","doi":"10.3390/cells11233834","title":"Delivery of Active AKT1 to Human Cells","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"AKT1; Phosphorylation; Cell biology; Transfection; Biology; Kinase; Protein kinase B; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003197085,0.0005714564,0.0003484345,0.0002759082,0.0002413911,0.0005118147,0.0002779472,0.0004573403,0.002444792],"category_scores_gemma":[0.0001167209,0.0002036571,0.0002861753,0.0003392285,0.0002094868,0.0002121081,0.0002495452,0.000762816,0.001599883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004471502,"about_ca_system_score_gemma":0.000362447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004844412,"about_ca_topic_score_gemma":0.0005446172,"domain_scores_codex":[0.9997399,0.00003109906,0.00002379925,0.00008815287,0.00007101884,0.00004592962],"domain_scores_gemma":[0.9999462,0.00001224401,0.00001068976,0.00001261203,0.000009019087,0.000009140146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001684407,0.00005831378,0.00008205011,0.0001264392,0.00001435076,0.00007787359,0.00007120361,0.0001716476,0.9918498,0.001026932,0.0008007077,0.005552246],"study_design_scores_gemma":[0.00004346867,0.0002458045,0.0004539173,0.00001229072,0.00002729536,0.0002611032,0.00001562672,0.0007524843,0.9712756,0.0001137166,0.02679188,0.000006748362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8004007,0.01569521,0.138319,0.0009521622,0.0008751904,0.001332179,0.01279736,0.001604038,0.02802407],"genre_scores_gemma":[0.919644,0.006966241,0.04527739,0.0003190091,0.00006962773,0.0007105681,0.008261578,0.0001640409,0.01858757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002444792,"threshold_uncertainty_score":0.008178711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014190276917181,"score_gpt":0.2485863312061706,"score_spread":0.2384444284369988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}