{"id":"W4311087906","doi":"10.1016/j.psyneuen.2022.106000","title":"Reduced epigenetic age in older adults who volunteer","year":2022,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute on Aging; Michael Smith Health Research BC; University of Michigan","keywords":"dNaM; Epigenetics; Longevity; Demography; Confounding; Gerontology; Health and Retirement Study; DNA methylation; Medicine; Biology; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007889627,0.0001950237,0.0002042369,0.0001781273,0.0001250276,0.00001184027,0.0003394064,0.00005233129,0.0001922143],"category_scores_gemma":[0.00005270862,0.0002298751,0.00008998107,0.0002329773,0.0000693651,0.000002329803,0.0002732853,0.0002787259,0.0000209237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002479277,"about_ca_system_score_gemma":0.00003511036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000459118,"about_ca_topic_score_gemma":0.0001144641,"domain_scores_codex":[0.9980226,0.0002838033,0.000340024,0.0006752099,0.0001690625,0.0005093454],"domain_scores_gemma":[0.9992276,0.00001753296,0.00009487216,0.000549299,0.0000353784,0.00007524493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009185011,0.0008766288,0.07883239,0.00003935492,0.00006067693,0.0004951921,0.0006607246,0.001587932,0.8865579,0.0003216675,0.006579588,0.0230695],"study_design_scores_gemma":[0.005548972,0.001852446,0.5527031,0.00001748532,0.00002350125,0.0001959642,0.0003368638,0.0002109736,0.1522018,0.0008275934,0.2852407,0.0008404827],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927194,0.002814157,0.0001773694,0.0006250141,0.0009772307,0.000360965,0.00001537415,0.00002091971,0.002289632],"genre_scores_gemma":[0.9961892,0.0007139089,0.000165001,0.0005260862,0.0001445945,0.0002155648,0.000112723,0.00004520799,0.001887739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.734356,"threshold_uncertainty_score":0.9374036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009320473178182916,"score_gpt":0.259388752576573,"score_spread":0.2500682793983901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}