{"id":"W4311192892","doi":"10.1097/tp.0000000000004339","title":"Diagnostic Potential of Minimally Invasive Biomarkers: A Biopsy-centered Viewpoint From the Banff Minimally Invasive Diagnostics Working Group","year":2022,"lang":"en","type":"review","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Astellas Pharma; Sangamo Therapeutics; CareDx; Veloxis Pharmaceuticals; CSL Behring","keywords":"Medicine; Kidney transplantation; Transplantation; Diagnostic biomarker; Minimally invasive procedures; Pathology; Biomarker; Internal medicine; Diagnostic accuracy; Surgery; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002761252,0.000781855,0.001916644,0.0003133132,0.0002195157,0.00006424896,0.0004485284,0.0003137846,0.0005836271],"category_scores_gemma":[0.0003457356,0.0005509766,0.001126019,0.0005969396,0.0001655568,0.0001216881,0.00004227392,0.0005226493,0.00007255458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002092248,"about_ca_system_score_gemma":0.0005420534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000323732,"about_ca_topic_score_gemma":0.0002964651,"domain_scores_codex":[0.9957561,0.0005748413,0.001600326,0.0007774887,0.000852906,0.0004382743],"domain_scores_gemma":[0.9881762,0.009980482,0.001034737,0.0005342849,0.00008795458,0.0001863414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.006573599,0.003791436,0.01942995,0.1743186,0.02898841,0.02240802,0.008429578,0.00002726746,0.0007748043,0.0002527411,0.000525618,0.73448],"study_design_scores_gemma":[0.03814671,0.004822964,0.09547926,0.4760392,0.182741,0.005884649,0.001901218,0.00003334407,0.0007103773,0.0003934194,0.1897249,0.004122871],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006732925,0.9840388,0.000302416,0.000186348,0.000819128,0.003577917,0.003988598,0.00007632529,0.0002775683],"genre_scores_gemma":[0.006530455,0.9705911,0.001323079,0.0002241435,0.0002105174,0.0005193121,0.02045264,0.0001203874,0.00002831721],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7303572,"threshold_uncertainty_score":0.9996942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05785540057446404,"score_gpt":0.304878810442911,"score_spread":0.247023409868447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}