{"id":"W4311200937","doi":"10.2174/1389557523666221207155909","title":"The Role of Genetics and Synergistic Effect of Targeting Common GeneticMutations in Acute Lymphoblastic Leukemia (ALL)","year":2022,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Lymphoblastic Leukemia; Genetics; Mutation; Biology; Cancer research; Medicine; Leukemia; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002906022,0.0004487312,0.0007261104,0.0009918347,0.0001492311,0.0006152009,0.0004523467,0.000571362,0.002981069],"category_scores_gemma":[0.0002661998,0.0001635835,0.0004150229,0.0008248637,0.0002668603,0.0005682516,0.0004019612,0.001012295,0.001025183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003050579,"about_ca_system_score_gemma":0.0004304937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003993448,"about_ca_topic_score_gemma":0.0008870647,"domain_scores_codex":[0.9998972,0.00002239996,0.00001095848,0.00001911969,0.00003444004,0.00001586131],"domain_scores_gemma":[0.9999169,0.00004001843,0.0000141136,0.0000032592,0.00001753442,0.000008244751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001661124,0.0001276681,0.0002944607,0.01870751,0.000140034,0.0003990176,0.00008629245,0.0006623431,0.01243151,0.006392525,0.01575836,0.9448342],"study_design_scores_gemma":[0.00004274576,0.0005348495,0.001515373,0.002192071,0.0002215931,0.002134978,0.00007015638,0.0002027241,0.005400006,0.002815956,0.9848433,0.00002625586],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007181328,0.9973546,0.0002121803,0.0002174284,0.0001312229,0.000008074761,0.00003332509,0.00001016317,0.001314914],"genre_scores_gemma":[0.003436915,0.9951975,0.0002739011,0.0001825657,0.00008014003,0.00001109763,0.00004907414,0.000002063853,0.0007667129],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002981069,"threshold_uncertainty_score":0.009972632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02163836644902219,"score_gpt":0.3429304732559673,"score_spread":0.3212921068069451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}