{"id":"W4311202297","doi":"10.1093/cid/ciac938","title":"Non-<i>Lactobacillus</i>-Dominant and Polymicrobial Vaginal Microbiomes Are More Common in Younger South African Women and Predictive of Increased Risk of Human Immunodeficiency Virus Acquisition","year":2022,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Microbiome; Medicine; Lactobacillus crispatus; Dysbiosis; Lactobacillus; Odds ratio; Hazard ratio; Confidence interval; Internal medicine; Incidence (geometry); Coinfection; Immunology; Human immunodeficiency virus (HIV); Biology; Bacteria; Disease; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006034945,0.0002894386,0.0003159401,0.0004665306,0.000427692,0.0005616878,0.0001884344,0.0002524425,0.003508476],"category_scores_gemma":[0.001478938,0.0001686724,0.0003524181,0.0006193913,0.0002566859,0.0002979275,0.0004206632,0.0003708187,0.0001499006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000179188,"about_ca_system_score_gemma":0.000262486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002561584,"about_ca_topic_score_gemma":0.002900812,"domain_scores_codex":[0.9997513,0.00007035697,0.00002356434,0.0000586203,0.00004180966,0.0000543222],"domain_scores_gemma":[0.9989861,0.0001261168,0.0006918226,0.00003609554,0.00005403091,0.0001058052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004086901,0.0000264046,0.9929107,0.0000751414,0.00006111639,0.0001107657,0.0001790887,0.00001816625,0.002143615,0.00001982411,0.0001165636,0.003929939],"study_design_scores_gemma":[0.000010137,0.0001247276,0.998369,0.00003619661,0.00004363585,0.0003853317,0.0003603683,0.00004784072,0.0002244386,0.00002796927,0.0003680132,0.000002256057],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987468,0.0005974852,0.00005158413,0.00005034922,0.000005573313,0.00001137239,0.0001981711,0.000001897883,0.0003367187],"genre_scores_gemma":[0.9993063,0.0002824799,0.0001114612,0.00003107111,0.000008495324,0.000009172619,0.0001346664,0.000001632654,0.0001147335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003508476,"threshold_uncertainty_score":0.01173705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01314180204936546,"score_gpt":0.3044046998973838,"score_spread":0.2912628978480183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}