{"id":"W4311202297","doi":"10.1093/cid/ciac938","title":"Non-<i>Lactobacillus</i>-Dominant and Polymicrobial Vaginal Microbiomes Are More Common in Younger South African Women and Predictive of Increased Risk of Human Immunodeficiency Virus Acquisition","year":2022,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Microbiome; Medicine; Lactobacillus crispatus; Dysbiosis; Lactobacillus; Odds ratio; Hazard ratio; Confidence interval; Internal medicine; Incidence (geometry); Coinfection; Immunology; Human immunodeficiency virus (HIV); Biology; Bacteria; Disease; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00105957,0.000244176,0.0007942675,0.0004878645,0.0004611129,0.00001691924,0.0001931181,0.0001529779,0.0002240629],"category_scores_gemma":[0.0003974752,0.0002348282,0.0001606016,0.000494562,0.001964523,0.0001586178,0.0004709304,0.0007063862,0.00000453953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001916449,"about_ca_system_score_gemma":0.0001441349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001482484,"about_ca_topic_score_gemma":0.00003868739,"domain_scores_codex":[0.996865,0.001151463,0.0008565344,0.0006224071,0.00009476407,0.0004098487],"domain_scores_gemma":[0.9980697,0.0005850272,0.0006591592,0.0004528687,0.0001607994,0.00007245339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001129948,0.002549767,0.7662883,0.00006526821,0.0002771853,0.000007396161,0.001304447,0.00003217493,0.2277876,0.00001736964,0.00004499491,0.0004954638],"study_design_scores_gemma":[0.003659629,0.002394668,0.982318,0.00003960314,0.0001500733,0.00003866672,0.002443258,0.00000834571,0.008372979,0.0002959282,0.00006329653,0.0002155505],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945575,0.001912455,0.00001403355,0.00002835315,0.0002318544,0.0006307695,0.002525859,0.00003138354,0.00006780757],"genre_scores_gemma":[0.9993668,0.0002074727,0.000001599605,0.00003199772,0.00002737813,0.0001480502,0.0001516826,0.0000233301,0.00004173235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2194147,"threshold_uncertainty_score":0.9576016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01314180204936546,"score_gpt":0.3044046998973838,"score_spread":0.2912628978480183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}