{"id":"W4311203424","doi":"10.1042/ebc20220047","title":"How viral proteins bind short linear motifs and intrinsically disordered domains","year":2022,"lang":"en","type":"article","venue":"Essays in Biochemistry","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK","keywords":"Viral protein; Biology; Intrinsically disordered proteins; Globular protein; Computational biology; Viral entry; Cell biology; Protein–protein interaction; Viral replication; Virus; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002559659,0.0003712194,0.0002739232,0.0001830556,0.000375469,0.0008738709,0.0003237836,0.0006802866,0.001526798],"category_scores_gemma":[0.0003113562,0.0002776389,0.0002697655,0.0001531797,0.0004557584,0.0009139656,0.000432847,0.000596216,0.001198015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004291134,"about_ca_system_score_gemma":0.0002168672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005366735,"about_ca_topic_score_gemma":0.0007075061,"domain_scores_codex":[0.9998412,0.00003789139,0.00000784459,0.00002629585,0.00004726727,0.00003935867],"domain_scores_gemma":[0.9999303,0.00002635275,0.00001305029,0.000005831836,0.00001257418,0.00001201127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001848944,0.00006645175,0.001701768,0.001052554,0.00006757653,0.001057248,0.0005060792,0.002138133,0.9018059,0.03925752,0.002970743,0.04919112],"study_design_scores_gemma":[0.00003592903,0.0003317992,0.003571157,0.0002410596,0.00008296847,0.002160229,0.000643493,0.005534387,0.700223,0.01982037,0.2672917,0.00006404951],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.658706,0.1905473,0.05937722,0.003816361,0.001344852,0.0001283419,0.0003222174,0.0004715869,0.08528602],"genre_scores_gemma":[0.8991857,0.05646366,0.01610996,0.001435901,0.0001811804,0.00006402113,0.0002795269,0.00008869621,0.02619153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001526798,"threshold_uncertainty_score":0.005107641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005060635315352205,"score_gpt":0.2089869910470735,"score_spread":0.2039263557317213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}