{"id":"W4311220073","doi":"10.1007/s13555-022-00861-4","title":"Long-Term Health-Related Quality of Life in Patients with Plaque Psoriasis Treated with Certolizumab Pegol: Three-Year Results from Two Randomised Phase 3 Studies (CIMPASI-1 and CIMPASI-2)","year":2022,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"LEO Pharma; UCB Pharma; Regeneron Pharmaceuticals; Sun Pharma; Valeant Pharmaceuticals International; Case Western Reserve University; XBiotech; Celgene; Incyte; Dermira; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Certolizumab pegol; Medicine; Plaque psoriasis; Psoriasis; Term (time); Quality of life (healthcare); Internal medicine; Dermatology; Adalimumab; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001674565,0.0003497409,0.001266146,0.000199715,0.0003751247,0.000007973679,0.0001318781,0.000166086,0.00009214835],"category_scores_gemma":[0.0000369356,0.0002475063,0.000065628,0.0002369585,0.0004122827,0.00008811443,0.00005896448,0.0002619882,0.00000307091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000411859,"about_ca_system_score_gemma":0.0001037287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001167464,"about_ca_topic_score_gemma":0.000831215,"domain_scores_codex":[0.9968801,0.001322102,0.0008134637,0.0005241375,0.00007647837,0.0003837288],"domain_scores_gemma":[0.9983326,0.0006567661,0.000561277,0.0003172542,0.00007260929,0.00005945472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2028315,0.0009204362,0.7809758,0.00002471701,0.002375725,0.00008998753,0.003005535,0.000002682375,0.0001686667,0.00007381343,0.00005917969,0.009471931],"study_design_scores_gemma":[0.3948253,0.00192801,0.6008879,0.00004377268,0.0001241711,0.0001827744,0.0005292158,0.000002713938,0.0009779573,0.0001219465,0.00006078292,0.0003154247],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790267,0.01832048,0.000004542432,0.0008280104,0.0001371573,0.0009560548,0.0006517068,0.00005153685,0.00002381393],"genre_scores_gemma":[0.9967496,0.001918009,0.0000230956,0.00008490822,0.000007576087,0.0001333729,0.001034849,0.00002528972,0.00002331991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1919938,"threshold_uncertainty_score":0.9999977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03323950638803691,"score_gpt":0.288253045115014,"score_spread":0.2550135387269771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}