{"id":"W4311281304","doi":"10.1111/imcb.12614","title":"Receptor‐mediated effects of Δ<sup>9</sup>‐tetrahydrocannabinol and cannabidiol on the inflammatory response of alveolar macrophages","year":2022,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; McGill University; Christie (Canada); AV&R (Canada); Université de Montréal; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cannabidiol; Proinflammatory cytokine; Cannabinoid; Tumor necrosis factor alpha; Alveolar macrophage; Immune system; Inflammation; Pharmacology; Chemistry; Tetrahydrocannabinol; Cytokine; Receptor; Immunology; Macrophage; Biology; Medicine; Cannabis; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002278134,0.0003036834,0.0002880457,0.0001881417,0.0001919037,0.0002097832,0.0002688189,0.0002852671,0.001777602],"category_scores_gemma":[0.0001642461,0.0001523768,0.00042383,0.0001396323,0.0002662336,0.0001793993,0.0001794462,0.0004711115,0.0005959859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002512888,"about_ca_system_score_gemma":0.0003072098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001229132,"about_ca_topic_score_gemma":0.001379765,"domain_scores_codex":[0.9997084,0.00006464038,0.00002927519,0.000033273,0.00006717474,0.00009717618],"domain_scores_gemma":[0.9998728,0.00003970662,0.00001882841,0.00001649846,0.00002679591,0.00002532465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005709782,0.0000333241,0.0001224095,0.0000430134,0.000004862132,0.00004086518,0.0000143304,0.00003812267,0.9985802,0.00002471833,0.00001668446,0.0005103907],"study_design_scores_gemma":[0.00004337798,0.0006873021,0.007146249,0.000008727126,0.00002291925,0.0001034838,0.0000982881,0.0005151419,0.9906127,0.00004613159,0.0007089291,0.00000668718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949487,0.001911716,0.001103192,0.0001077325,0.0000531775,0.00004010264,0.0004945231,0.00001868631,0.00132216],"genre_scores_gemma":[0.9944144,0.001026384,0.001637869,0.0001287788,0.00002241707,0.00008850375,0.0003822695,0.000007518688,0.002291765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001777602,"threshold_uncertainty_score":0.005946636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005055518696656638,"score_gpt":0.228854575696665,"score_spread":0.2237990570000083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}