{"id":"W4311445350","doi":"10.1111/bdi.13284","title":"Real‐world effectiveness of repeated ketamine infusions for treatment‐resistant bipolar depression","year":2022,"lang":"en","type":"article","venue":"Bipolar Disorders","topic":"Treatment of Major Depression","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health; Canadian Transplant Association; University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Hypomania; Bipolar disorder; Depression (economics); Treatment-resistant depression; Mania; Antidepressant; Ketamine; Anxiety; Medicine; Major depressive disorder; Psychiatry; Psychology; Internal medicine; Anesthesia; Mood","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00133612,0.0002060669,0.0004637391,0.0001197848,0.0002204075,0.0004137703,0.0003115266,0.0002288088,0.0007578377],"category_scores_gemma":[0.003773637,0.0001181666,0.0004038003,0.0001725648,0.0002503643,0.0001820101,0.0002228913,0.0003584996,0.0001055265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001110556,"about_ca_system_score_gemma":0.0007908854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005160074,"about_ca_topic_score_gemma":0.0152305,"domain_scores_codex":[0.9986897,0.0007959359,0.0001285779,0.0001111582,0.0001866568,0.00008799328],"domain_scores_gemma":[0.9979904,0.0004229571,0.001109804,0.0001005302,0.0001448977,0.0002315361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.119511,0.01292651,0.4105991,0.002022502,0.002955449,0.0006774997,0.0009312424,0.003636417,0.02069891,0.0001761155,0.004826299,0.4210391],"study_design_scores_gemma":[0.01168448,0.1120166,0.8630178,0.000208393,0.001099796,0.0008427835,0.0005456429,0.003122888,0.00297146,0.0001381341,0.004286948,0.00006504156],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969894,0.001688347,0.0002032293,0.000129626,0.00001580657,0.0001391425,0.0002011724,0.0000124752,0.0006207242],"genre_scores_gemma":[0.9985871,0.0006431426,0.0003322423,0.00007014835,0.00002711829,0.0001035815,0.0001568736,0.000001769466,0.00007794184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005160074,"threshold_uncertainty_score":0.01026005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379868742722801,"score_gpt":0.2809331751155404,"score_spread":0.2671344876883124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}