{"id":"W4311480480","doi":"10.1111/dom.14943","title":"Achievement of glycaemic targets with weight loss and without hypoglycaemia in type 2 diabetes with the once‐weekly glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 receptor agonist tirzepatide: A <i>post hoc</i> analysis of the <scp>SURPASS</scp> ‐1 to ‐5 studies","year":2022,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trillium Health Centre; University of Toronto","funders":"Eli Lilly and Company; American Diabetes Association","keywords":"Semaglutide; Type 2 diabetes; Medicine; Weight loss; Internal medicine; Glucagon-like peptide 1 receptor; Placebo; Basal insulin; Basal (medicine); Hypoglycemia; Exenatide; Clinical endpoint; Endocrinology; Post-hoc analysis; Randomized controlled trial; Diabetes mellitus; Insulin; Agonist; Obesity; Liraglutide; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005974316,0.001028991,0.002338382,0.0003737837,0.0002019707,0.001147526,0.0006114729,0.0007621584,0.00186362],"category_scores_gemma":[0.002998067,0.0004272107,0.004689379,0.0003824763,0.0006243379,0.000784952,0.0004833036,0.001570709,0.0001956042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005219081,"about_ca_system_score_gemma":0.0009138937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006026464,"about_ca_topic_score_gemma":0.001619078,"domain_scores_codex":[0.9974204,0.001758863,0.0002096332,0.0002039985,0.0002264309,0.0001807587],"domain_scores_gemma":[0.9973468,0.001075094,0.0007561152,0.0002444801,0.0002169126,0.0003605967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.9565431,0.002312409,0.005307576,0.001102858,0.009599608,0.00003638464,0.00008070231,0.0005165344,0.004573807,0.00006253403,0.0002185952,0.01964578],"study_design_scores_gemma":[0.3586535,0.5430627,0.06349115,0.0002507126,0.02394736,0.0001855262,0.0001589633,0.001467533,0.0067002,0.0002610691,0.001755719,0.00006545533],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927995,0.004307314,0.0005441246,0.000101068,0.00007255818,0.000853318,0.0004083921,0.00001979422,0.0008938599],"genre_scores_gemma":[0.9955894,0.001798583,0.0006877851,0.0001320666,0.00008081148,0.0006256319,0.0005058073,0.00001010691,0.0005698131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005974316,"threshold_uncertainty_score":0.03159559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00725095975743336,"score_gpt":0.2177150876792218,"score_spread":0.2104641279217885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}