{"id":"W4311486730","doi":"10.1002/alz.12885","title":"AD and non‐AD mediators of the pathway between the <i>APOE</i> genotype and cognition","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Toronto Rehabilitation Institute; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; University of California, San Francisco; University of California, Davis; National Institute on Aging; National Institutes of Health","keywords":"Neuropathology; Apolipoprotein E; Dementia; Cerebral amyloid angiopathy; Psychology; Cognition; Neuroscience; Cognitive decline; Dementia with Lewy bodies; Disease; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003036002,0.0007492783,0.000429653,0.0009106632,0.0003322509,0.0009774524,0.000670889,0.0004180992,0.004622343],"category_scores_gemma":[0.0065953,0.0002566046,0.001142404,0.000742546,0.0006741976,0.0004857953,0.0007680913,0.0005427711,0.0002123329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003671263,"about_ca_system_score_gemma":0.0009221401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005941661,"about_ca_topic_score_gemma":0.004392641,"domain_scores_codex":[0.9989514,0.0005689136,0.00006648766,0.0002074418,0.00009498338,0.0001107069],"domain_scores_gemma":[0.9951137,0.002425553,0.001478165,0.0004469071,0.0002571808,0.0002784739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007979214,0.0000819781,0.9879304,0.0001151573,0.001239765,0.0001847368,0.0001824613,0.0002355429,0.0004760647,0.000564944,0.0001532563,0.008037901],"study_design_scores_gemma":[0.00004963236,0.0002797266,0.9928873,0.00007172384,0.001415424,0.0002939547,0.0001757639,0.0008334219,0.0005843915,0.00274642,0.000648806,0.00001340672],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908825,0.004354014,0.00163466,0.0005122227,0.00002295102,0.00003711828,0.001098677,0.00002023331,0.001437685],"genre_scores_gemma":[0.9982923,0.0004735294,0.0005450757,0.00006246485,0.00002207283,0.00002263604,0.000296074,0.000003020091,0.0002828474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005941661,"threshold_uncertainty_score":0.01605612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01963536908336243,"score_gpt":0.2730160654972135,"score_spread":0.253380696413851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}