{"id":"W4311515325","doi":"10.1016/j.scib.2022.12.006","title":"Alzheimer’s disease: current status and perspective","year":2022,"lang":"en","type":"article","venue":"Science Bulletin","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Key Scientific Instrument and Equipment Development Projects of China; Beijing Municipal Science and Technology Commission; National Natural Science Foundation of China","keywords":"Perspective (graphical); Current (fluid); Disease; Alzheimer's disease; Psychology; Medicine; Computer science; Internal medicine; Engineering; Artificial intelligence; Electrical engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005607591,0.00006644698,0.00007656089,0.0001584991,0.0005226955,0.00004501182,0.0001059738,0.000003855617,0.004268643],"category_scores_gemma":[0.0001556181,0.00005803244,0.00002757475,0.0003990992,0.0005503371,0.00003605592,0.0003564603,0.000182829,0.00007969254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001415333,"about_ca_system_score_gemma":0.0005003511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003891537,"about_ca_topic_score_gemma":3.194967e-7,"domain_scores_codex":[0.9982486,0.00004483633,0.0000733101,0.0003515487,0.000888451,0.0003932985],"domain_scores_gemma":[0.9992723,0.0000217928,0.00002101042,0.0001346358,0.0001572486,0.000392958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001104104,0.00179084,0.7662988,0.00005873083,0.00007327578,0.0002699127,0.002753277,0.000005717436,0.003568187,0.02669098,0.03047077,0.1669154],"study_design_scores_gemma":[0.0007235891,0.0003818948,0.6634237,0.00001239952,0.00005430865,0.00001423732,0.003369421,0.00006575013,0.0002366615,0.0005798969,0.3310424,0.00009568608],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9469248,0.01234884,0.00002540243,0.01899055,0.0002593637,0.0007316034,0.00002897088,0.00005267209,0.02063778],"genre_scores_gemma":[0.9984362,0.0001556667,0.00006751413,0.0003899013,0.00003488345,0.00008172758,0.000004190844,0.000005182875,0.0008247765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3005717,"threshold_uncertainty_score":0.9966416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02555774934621656,"score_gpt":0.3543251268570798,"score_spread":0.3287673775108632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}