{"id":"W4311521053","doi":"10.3390/v14122710","title":"U5 snRNP Core Proteins Are Key Components of the Defense Response against Viral Infection through Their Roles in Programmed Cell Death and Interferon Induction","year":2022,"lang":"en","type":"article","venue":"Viruses","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"snRNP; Spliceosome; Biology; RNA splicing; Necroptosis; Ribonucleoprotein; Small nuclear ribonucleoprotein; Cell biology; Interferon; Viral replication; RNA; Programmed cell death; Virology; Genetics; Virus; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000169958,0.0004419879,0.0003533028,0.0003097553,0.0002886552,0.0004268206,0.0001968739,0.000315535,0.0006828637],"category_scores_gemma":[0.0001585409,0.0001220381,0.0003076627,0.0002750092,0.000239098,0.0002866824,0.0002903822,0.0002668336,0.0003535296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003037749,"about_ca_system_score_gemma":0.0001963882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005732461,"about_ca_topic_score_gemma":0.0007500073,"domain_scores_codex":[0.9997802,0.00003203844,0.00002649504,0.00005398308,0.00006820379,0.00003912978],"domain_scores_gemma":[0.9998872,0.0000139483,0.00004709441,0.00001177469,0.00002128077,0.00001864498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001650601,0.00001504194,0.001882391,0.0001474966,0.00001682782,0.0002066527,0.00004539695,0.0001469793,0.9827867,0.0005902824,0.0001065355,0.01389062],"study_design_scores_gemma":[0.000008975579,0.0002767294,0.02251933,0.00004523579,0.00005604032,0.001236437,0.0001169977,0.001793168,0.9543232,0.0006869691,0.01891671,0.00002010953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9320318,0.03346206,0.02662732,0.0001348213,0.00009996884,0.00008275932,0.001150886,0.000412079,0.005998322],"genre_scores_gemma":[0.9815963,0.005288024,0.009450214,0.00009022574,0.00002815121,0.000028837,0.001288872,0.00002775651,0.002201563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006828637,"threshold_uncertainty_score":0.002284408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04722925033566178,"score_gpt":0.2855561663248882,"score_spread":0.2383269159892264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}