{"id":"W4311582042","doi":"10.1038/s41598-022-25134-0","title":"Long-term durability of immune responses to the BNT162b2 and mRNA-1273 vaccines based on dosage, age and sex","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; National Research Council Canada; University of Manitoba; York University","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Immunogenicity; Immunity; Vaccination; Immune system; Humoral immunity; Medicine; Immunology; Clinical trial; Vaccine efficacy; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002096691,0.0003099656,0.0003630222,0.0002231122,0.0001410077,0.0004401485,0.0003710853,0.0005569272,0.001507015],"category_scores_gemma":[0.003416191,0.0002221127,0.0005317939,0.0001428957,0.0003425649,0.0007520771,0.0003974962,0.0007666383,0.000401985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006576847,"about_ca_system_score_gemma":0.0005959248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001415828,"about_ca_topic_score_gemma":0.001409941,"domain_scores_codex":[0.9995296,0.0001022677,0.00002159013,0.0001055548,0.00008046562,0.0001605749],"domain_scores_gemma":[0.997764,0.00112873,0.0007089081,0.0001350162,0.0001297013,0.0001337715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004138516,0.000917375,0.371168,0.0003928126,0.0005408942,0.000685148,0.0003596085,0.3299564,0.2274102,0.004654099,0.0009167157,0.0588603],"study_design_scores_gemma":[0.0001414654,0.009260042,0.3036574,0.0001175849,0.0005822683,0.001161569,0.0004649549,0.581707,0.09393173,0.005158712,0.003695672,0.0001216529],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903528,0.0005864447,0.006779789,0.0001471812,0.0000118999,0.00004326481,0.0003629572,0.00002277902,0.001693003],"genre_scores_gemma":[0.997732,0.0001232369,0.0007597833,0.00006370654,0.000002831441,0.00004124501,0.0002448406,0.000004536948,0.001027645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002096691,"threshold_uncertainty_score":0.01108855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03518360737136538,"score_gpt":0.3424960199509642,"score_spread":0.3073124125795988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}