{"id":"W4311589886","doi":"10.1016/j.devcel.2022.11.007","title":"Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation","year":2022,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Hospital; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; University of California, San Diego; National Institutes of Health; Japan Heart Foundation; Uehara Memorial Foundation; Howard Hughes Medical Institute","keywords":"Biology; Progenitor cell; Cell biology; Linoleic acid; CD36; Adipose tissue; Lipolysis; Arachidonic acid; Endocrinology; Internal medicine; Fatty acid; Biochemistry; Stem cell; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001244901,0.0002350982,0.0003072523,0.0001696797,0.0003986648,0.00002642544,0.0001501339,0.00006951112,0.001404952],"category_scores_gemma":[0.000009887301,0.0002308649,0.0001029282,0.0003071485,0.00004163038,0.0001091817,0.0002038873,0.0003056568,0.0004201746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001823791,"about_ca_system_score_gemma":0.0002741533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009834268,"about_ca_topic_score_gemma":0.000003621473,"domain_scores_codex":[0.9983196,0.00006923411,0.0003437832,0.0003946261,0.0004894555,0.0003833626],"domain_scores_gemma":[0.9994282,0.00001266214,0.0001125669,0.0001902832,0.00005263774,0.0002037219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002240608,0.0005929748,0.009319252,0.00009705358,0.00006798896,0.0001193296,0.006414043,0.000002701592,0.970424,0.00002030154,0.002916714,0.009801582],"study_design_scores_gemma":[0.001541419,0.0001839356,0.006530148,0.00000879245,0.0001138956,0.00007681104,0.001790289,0.00002119627,0.8771045,0.00001588354,0.1123471,0.0002660023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986258,0.001986979,0.00008352219,0.0002164147,0.000475466,0.0009178028,0.00001795289,0.000134618,0.009909273],"genre_scores_gemma":[0.969314,0.00006767033,0.007498938,0.000732895,0.000334053,0.0002975539,0.0003806719,0.0000496153,0.02132462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1094304,"threshold_uncertainty_score":0.9995079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01319029591104377,"score_gpt":0.2312340747807017,"score_spread":0.218043778869658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}