{"id":"W4311619446","doi":"10.3389/fimmu.2022.1041010","title":"Hematologic dysfunction in cancer: Mechanisms, effects on antitumor immunity, and roles in disease progression","year":2022,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Leukemia and Lymphoma Society of Canada; Canada Research Chairs; McGill University","keywords":"Haematopoiesis; Cancer; Myelopoiesis; Immunology; Disease; Immune system; Cancer stem cell; Medicine; Epigenetics; Immune Dysfunction; Biology; Cancer research; Stem cell; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000504923,0.0007128522,0.001071177,0.001361305,0.0002331821,0.0009054138,0.0006710021,0.001028488,0.002206824],"category_scores_gemma":[0.0005513445,0.0001691606,0.0003675047,0.001141797,0.0006138026,0.001003388,0.0006872185,0.001836664,0.001180776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006138252,"about_ca_system_score_gemma":0.0007861715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005912664,"about_ca_topic_score_gemma":0.0009018849,"domain_scores_codex":[0.9998277,0.00003705679,0.00002119579,0.00002706991,0.00006333237,0.00002354889],"domain_scores_gemma":[0.9997939,0.00009124833,0.00002729351,0.000007107359,0.00005111202,0.00002926809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001239842,0.00005484539,0.0003320369,0.009913206,0.0000704474,0.0002649767,0.00005864858,0.0003814708,0.003379088,0.005680562,0.02862968,0.9511113],"study_design_scores_gemma":[0.00001630237,0.0001366916,0.001434939,0.001979324,0.00007414096,0.002156822,0.00006369298,0.0001015519,0.0009122738,0.0031901,0.9899156,0.00001852543],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009523809,0.9988077,0.0001068572,0.0002605238,0.0002106525,0.000002178816,0.000009349391,0.000005404231,0.0005022408],"genre_scores_gemma":[0.0008827319,0.9980744,0.0001018033,0.0001838928,0.0002789873,0.000004199353,0.00002181062,0.000001196291,0.0004508975],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002206824,"threshold_uncertainty_score":0.007382572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01588793272144773,"score_gpt":0.2871616123761694,"score_spread":0.2712736796547217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}